CHEBI:4754 - econazole

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ChEBI Name econazole
ChEBI ID CHEBI:4754
Definition A racemate composed of equimolar amounts of (R)- and (S)-econazole. Used (as its nitrate salt) to treat skin infections such as athlete's foot, jock itch, ringworm and other fungal skin infections.
Stars This entity has been manually annotated by the ChEBI Team.
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Formula C18H15Cl3N2O
Net Charge 0
Average Mass 381.68400
Monoisotopic Mass 380.02500
Roles Classification
Biological Role(s): antifungal drug
Any antifungal agent used to prevent or treat fungal infections in humans or animals.
(via imidazole antifungal drug )
(via conazole antifungal drug )
antifungal agent
An antimicrobial agent that destroys fungi by suppressing their ability to grow or reproduce.
(via imidazole antifungal agent )
(via conazole antifungal agent )
ergosterol biosynthesis inhibitor
Any compound that inhibits one or more steps in the pathway leading to the synthesis of ergosterol.
(via conazole antifungal agent )
Application(s): antifungal drug
Any antifungal agent used to prevent or treat fungal infections in humans or animals.
(via imidazole antifungal drug )
(via conazole antifungal drug )
View more via ChEBI Ontology
ChEBI Ontology
Outgoing econazole (CHEBI:4754) has part (R)-econazole (CHEBI:82877)
econazole (CHEBI:4754) has part (S)-econazole (CHEBI:82872)
econazole (CHEBI:4754) is a conazole antifungal drug (CHEBI:87071)
econazole (CHEBI:4754) is a imidazole antifungal drug (CHEBI:87069)
econazole (CHEBI:4754) is a racemate (CHEBI:60911)
Incoming econazole nitrate (CHEBI:4755) has part econazole (CHEBI:4754)
IUPAC Name
rac-1-{2-(4-chlorobenzyloxy)-2-(2,4-dichlorophenyl)ethyl}-1H-imidazole
Synonyms Sources
(±)-econazole ChEBI
(+-)-Econazole ChemIDplus
(RS)-econazole ChEBI
1-(2,4-Dichloro-beta-((p-chlorobenzyl)oxy)phenethyl)imidazole ChemIDplus
Econazole KEGG COMPOUND
rac-econazole ChEBI
Manual Xrefs Databases
C08068 KEGG COMPOUND
D03936 KEGG DRUG
DB01127 DrugBank
Econazole Wikipedia
HMDB0015259 HMDB
View more database links
Registry Numbers Types Sources
27220-47-9 CAS Registry Number ChemIDplus
964150 Reaxys Registry Number Reaxys
Citations Waiting for Citations Types Sources
11065186 PubMed citation Europe PMC
15094063 PubMed citation Europe PMC
24374794 PubMed citation Europe PMC
24530389 PubMed citation Europe PMC
Last Modified
22 February 2017