CHEBI:83309 - olodaterol hydrochloride

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ChEBI Name olodaterol hydrochloride
ChEBI ID CHEBI:83309
Definition A hydrochloride obtained by combining olodaterol with one equivalent of hydrochloric acid. Used for long-term treatment of airflow obstruction in patients with chronic obstructive pulmonary disease including chronic bronchitis and/or emphysema.
Stars This entity has been manually annotated by the ChEBI Team.
Supplier Information eMolecules:3714906
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Alectinib (INN), sold under the brand name Alecensa, is an anticancer medication that is used to treat non-small-cell lung cancer (NSCLC). It blocks the activity of anaplastic lymphoma kinase (ALK). It is taken by mouth. It was developed by Chugai Pharmaceutical Co. Japan, which is part of the Hoffmann-La Roche group. The most common side effects include constipation, muscle pain and edema (swelling) including of the ankles and feet, the face, the eyelids and the area around the eyes. Alectinib was approved for medical use in Japan in 2014, the United States in 2015, Canada in 2016, Australia in 2017, the European Union in 2017, and the United Kingdom in 2021.
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Formula C21H27ClN2O5
Net Charge 0
Average Mass 422.90200
Monoisotopic Mass 422.16085
InChI InChI=1S/C21H26N2O5.ClH/c1-21(2,10-13-4-6-15(27-3)7-5-13)22-11-18(25)16-8-14(24)9-17-20(16)28-12-19(26)23-17;/h4-9,18,22,24-25H,10-12H2,1-3H3,(H,23,26);1H/t18-;/m0./s1
InChIKey KCEHVJZZIGJAAW-FERBBOLQSA-N
SMILES Cl.COc1ccc(CC(C)(C)NC[C@H](O)c2cc(O)cc3NC(=O)COc23)cc1
Roles Classification
Biological Role(s): beta-adrenergic agonist
An agent that selectively binds to and activates beta-adrenergic receptors.
Application(s): beta-adrenergic agonist
An agent that selectively binds to and activates beta-adrenergic receptors.
bronchodilator agent
An agent that causes an increase in the expansion of a bronchus or bronchial tubes.
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ChEBI Ontology
Outgoing olodaterol hydrochloride (CHEBI:83309) has part olodaterol(1+) (CHEBI:83312)
olodaterol hydrochloride (CHEBI:83309) has role β-adrenergic agonist (CHEBI:35522)
olodaterol hydrochloride (CHEBI:83309) has role bronchodilator agent (CHEBI:35523)
olodaterol hydrochloride (CHEBI:83309) is a hydrochloride (CHEBI:36807)
Incoming Stiolto Respimat (CHEBI:90958) has part olodaterol hydrochloride (CHEBI:83309)
IUPAC Names
6-hydroxy-8-[(1R)-1-hydroxy-2-{[1-(4-methoxyphenyl)-2-methylpropan-2-yl]amino}ethyl]-2H-1,4-benzoxazin-3(4H)-one hydrochloride
N-[(2R)-2-hydroxy-2-(6-hydroxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-8-yl)ethyl]-1-(4-methoxyphenyl)-2-methylpropan-2-aminium chloride
Brand Name Source
STRIVERDI RESPIMAT ChEBI
Manual Xrefs Databases
D10020 KEGG DRUG
Olodaterol Wikipedia
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Registry Numbers Types Sources
12431872 Reaxys Registry Number Reaxys
869477-96-3 CAS Registry Number ChemIDplus
Last Modified
15 January 2016