CHEBI:135079 - reposal

Main ChEBI Ontology Automatic Xrefs Reactions Pathways Models
ChEBI Name reposal
ChEBI ID CHEBI:135079
Stars This entity has been manually annotated by a third party.
Supplier Information
Download Molfile XML SDF
Formula C14H18N2O3
Net Charge 0
Average Mass 262.305
Monoisotopic Mass 262.13174
InChI InChI=1S/C14H18N2O3/c1-2-14(11(17)15-13(19)16-12(14)18)10-6-8-3-4-9(5-8)7-10/h6,8-9H,2-5,7H2,1H3,(H2,15,16,17,18,19)
InChIKey MKELYWOVSPVORM-UHFFFAOYSA-N
SMILES C(C)C1(C(=O)NC(NC1=O)=O)C=2CC3CC(C2)CC3
Roles Classification
Biological Role(s): GABA modulator
A substance that does not act as agonist or antagonist but does affect the gamma-aminobutyric acid receptor-ionophore complex. GABA-A receptors appear to have at least three allosteric sites at which modulators act: a site at which benzodiazepines act by increasing the opening frequency of gamma-aminobutyric acid-activated chloride channels; a site at which barbiturates act to prolong the duration of channel opening; and a site at which some steroids may act.
(via barbiturates )
Application(s): GABA modulator
A substance that does not act as agonist or antagonist but does affect the gamma-aminobutyric acid receptor-ionophore complex. GABA-A receptors appear to have at least three allosteric sites at which modulators act: a site at which benzodiazepines act by increasing the opening frequency of gamma-aminobutyric acid-activated chloride channels; a site at which barbiturates act to prolong the duration of channel opening; and a site at which some steroids may act.
(via barbiturates )
View more via ChEBI Ontology
ChEBI Ontology
Outgoing reposal (CHEBI:135079) is a barbiturates (CHEBI:22693)
Synonym Source
reposamal DrugCentral
Manual Xref Database
3824 DrugCentral
View more database links
Registry Number Type Source
3625-25-0 CAS Registry Number DrugCentral
Last Modified
23 February 2017