A drug used for the treatment or prevention of cardiac arrhythmias. Anti-arrhythmia drugs may affect the polarisation-repolarisation phase of the action potential, its excitability or refractoriness, or impulse conduction or membrane responsiveness within cardiac fibres.
A class I anti-arrhythmic, moricizine acts on the heart muscle to improve the heart's rhythm. It has potent local anaesthetic activity and membrane stabilizing effect, and is used as the hydrochloride in the treatment of serious symptomatic ventricular arrhythmias.