Flavin mononucleotide (FMN), or riboflavin-5′-phosphate, is a biomolecule produced from riboflavin (vitamin B2) by the enzyme riboflavin kinase and functions as the prosthetic group of various oxidoreductases, including NADH dehydrogenase, as well as a cofactor in biological blue-light photo receptors. During the catalytic cycle, a reversible interconversion of the oxidized (FMN), semiquinone (FMNH•), and reduced (FMNH2) forms occurs in the various oxidoreductases. FMN is a stronger oxidizing agent than NAD and is particularly useful because it can take part in both one- and two-electron transfers. In its role as blue-light photo receptor, (oxidized) FMN stands out from the 'conventional' photo receptors as the signaling state and not an E/Z isomerization.
It is the principal form in which riboflavin is found in cells and tissues. It requires more energy to produce, but is more soluble than riboflavin. In cells, FMN occurs freely circulating but also in several covalently bound forms. Covalently or non-covalently bound FMN is a cofactor of many enzymes playing an important pathophysiological role in cellular metabolism. For example dissociation of flavin mononucleotide from mitochondrial complex I has been shown to occur during ischemia/reperfusion brain injury during stroke. |
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InChI=1S/C6H8O6.Na/c7-1-2(8)5-3(9)4(10)6(11)12-5;/h2,5,7-10H,1H2;/q;+1/p-1/t2-,5+;/m0./s1 |
PPASLZSBLFJQEF-RXSVEWSESA-M |
[Na+].O1C(=O)C(O)=C([O-])[C@]1([C@H](CO)O)[H] |
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Daphnia magna
(NCBI:txid35525)
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See:
Mixtures of similarly acting compounds in Daphnia magna: From gene to metabolite and beyondTine Vandenbrouck, Oliver A.H. Jones, Nathalie Dom, Julian L. Griffin, Wim De CoenEnvironment International 36 (2010) 254-268
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Arabidopsis thaliana
(NCBI:txid3702)
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See:
DOI
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Homo sapiens
(NCBI:txid9606)
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See:
DOI
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food antioxidant
An antioxidant that used as a food additives to help guard against food deterioration.
reducing agent
The element or compound in a reduction-oxidation (redox) reaction that donates an electron to another species.
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food antioxidant
An antioxidant that used as a food additives to help guard against food deterioration.
flour treatment agent
A food additive which is added to flour or dough to improve baking quality and/or colour.
coenzyme
A low-molecular-weight, non-protein organic compound participating in enzymatic reactions as dissociable acceptor or donor of chemical groups or electrons.
plant metabolite
Any eukaryotic metabolite produced during a metabolic reaction in plants, the kingdom that include flowering plants, conifers and other gymnosperms.
human metabolite
Any mammalian metabolite produced during a metabolic reaction in humans (Homo sapiens).
Daphnia magna metabolite
A Daphnia metabolite produced by the species Daphnia magna.
water-soluble vitamin (role)
Any vitamin that dissolves in water and readily absorbed into tissues for immediate use. Unlike the fat-soluble vitamins, they are not stored in the body and need to be replenished regularly in the diet and will rarely accumulate to toxic levels since they are quickly excreted from the body via urine.
(via vitamin C )
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food antioxidant
An antioxidant that used as a food additives to help guard against food deterioration.
flour treatment agent
A food additive which is added to flour or dough to improve baking quality and/or colour.
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View more via ChEBI Ontology
sodium (2R)-2-[(1S)-1,2-dihydroxyethyl]-4-hydroxy-5-oxo-2,5-dihydrofuran-3-olate
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ascorbate de sodium
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ChemIDplus
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natrii ascorbas
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ChemIDplus
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sodium ascorbate
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KEGG DRUG
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ascorbic acid sodium salt
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ChemIDplus
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L-ascorbic acid sodium salt
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ChemIDplus
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L-ascorbic acid, monosodium salt
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ChemIDplus
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monosodium L-ascorbate
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ChemIDplus
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sodium L-ascorbate
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ChEBI
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vitamin C sodium
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ChemIDplus
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vitamin C, sodium salt
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ChemIDplus
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134-03-2
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CAS Registry Number
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KEGG DRUG
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134-03-2
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CAS Registry Number
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ChemIDplus
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5465157
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Reaxys Registry Number
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Reaxys
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26386330
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Europe PMC
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26755225
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26818978
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