Dicycloverine, also known as dicyclomine, sold under the brand name Bentyl among others, is a medication that is used to treat spasms of the intestines such as those that occur in irritable bowel syndrome (IBS). It is taken by mouth or by injection into a muscle. While it has been used in baby colic and enterocolitis, evidence does not support these uses.
Common side effects include dry mouth, blurred vision, weakness, sleepiness, and lightheadedness. Serious side effects may include psychosis and breathing problems in babies. Use in pregnancy appears to be safe while use during breastfeeding is not recommended. How it works is not entirely clear.
Dicycloverine was approved for medical use in the United States in 1950. It is available as a generic medication. In 2022, it was the 176th most commonly prescribed medication in the United States, with more than 2 million prescriptions. |
Read full article at Wikipedia
|
InChI=1S/C19H35NO2/c1-3-20(4-2)15-16-22-18(21)19(13-9-6-10-14-19)17-11-7-5-8-12-17/h17H,3-16H2,1-2H3 |
CURUTKGFNZGFSE-UHFFFAOYSA-N |
CCN(CC)CCOC(=O)C1(CCCCC1)C1CCCCC1 |
|
Bronsted base
A molecular entity capable of accepting a hydron from a donor (Bronsted acid).
(via organic amino compound )
|
|
muscarinic antagonist
A drug that binds to but does not activate muscarinic cholinergic receptors, thereby blocking the actions of endogenous acetylcholine or exogenous agonists.
parasympatholytic
Any cholinergic antagonist that inhibits the actions of the parasympathetic nervous system. The major group of drugs used therapeutically for this purpose is the muscarinic antagonists.
|
|
muscarinic antagonist
A drug that binds to but does not activate muscarinic cholinergic receptors, thereby blocking the actions of endogenous acetylcholine or exogenous agonists.
antispasmodic drug
A drug that suppresses spasms. These are usually caused by smooth muscle contraction, especially in tubular organs. The effect is to prevent spasms of the stomach, intestine or urinary bladder.
parasympatholytic
Any cholinergic antagonist that inhibits the actions of the parasympathetic nervous system. The major group of drugs used therapeutically for this purpose is the muscarinic antagonists.
|
|
View more via ChEBI Ontology
2-(diethylamino)ethyl 1,1'-bi(cyclohexyl)-1-carboxylate
|
dicicloverina
|
ChemIDplus
|
dicycloverine
|
ChEBI
|
dicycloverine
|
ChEBI
|
dicycloverinum
|
ChemIDplus
|
2-(diethylamino)ethyl 1-cyclohexylcyclohexanecarboxylate
|
ChEMBL
|
Bicyclohexyl-1-carboxylic acid 2-diethylamino-ethyl ester
|
ChEMBL
|
DICYCLOMINE
|
ChEMBL
|
Dicyclomine
|
KEGG COMPOUND
|
Dicycloverin
|
KEGG COMPOUND
|
868
|
DrugCentral
|
C06951
|
KEGG COMPOUND
|
D07820
|
KEGG DRUG
|
DB00804
|
DrugBank
|
Dicyclomine
|
Wikipedia
|
LSM-3534
|
LINCS
|
US2474796
|
Patent
|
View more database links |
2282819
|
Beilstein Registry Number
|
Beilstein
|
77-19-0
|
CAS Registry Number
|
ChemIDplus
|
|