Hyperforin is a phytochemical produced by some of the members of the plant genus Hypericum, notably Hypericum perforatum (St John's wort). Hyperforin may be involved in the pharmacological effects of St. John's wort, specifically in its antidepressant effects. |
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InChI=1S/C20H25NO2S2/c1-14-7-11-24-18(14)17(19-15(2)8-12-25-19)6-4-10-21-9-3-5-16(13-21)20(22)23/h6-8,11-12,16H,3-5,9-10,13H2,1-2H3,(H,22,23)/t16-/m1/s1 |
PBJUNZJWGZTSKL-MRXNPFEDSA-N |
Cc1ccsc1C(=CCCN1CCC[C@H](C1)C(O)=O)c1sccc1C |
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Bronsted acid
A molecular entity capable of donating a hydron to an acceptor (Bronsted base).
(via oxoacid )
Bronsted base
A molecular entity capable of accepting a hydron from a donor (Bronsted acid).
(via organic amino compound )
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GABA reuptake inhibitor
A compound that inhibits the re-uptake of the neurotransmitter GABA from the synapse into the pre-synaptic neuron, so increasing the extracellular concentrations of the neurotransmitter and hence increasing neurotransmission.
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GABA reuptake inhibitor
A compound that inhibits the re-uptake of the neurotransmitter GABA from the synapse into the pre-synaptic neuron, so increasing the extracellular concentrations of the neurotransmitter and hence increasing neurotransmission.
anticonvulsant
A drug used to prevent seizures or reduce their severity.
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View more via ChEBI Ontology
(3R)-1-[4,4-bis(3-methyl-2-thienyl)but-3-en-1-yl]piperidine-3-carboxylic acid
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tiagabina
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ChemIDplus
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tiagabine
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WHO MedNet
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tiagabine
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ChemIDplus
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tiagabinum
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ChemIDplus
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(−)-(R)-1-(4,4-bis(3-methyl-2-thienyl)-3-butenyl)nipecotic acid
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ChemIDplus
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(−)-(R)-1-[4,4-bis(3-methyl-2-thienyl)-3-butenyl]nipecotic acid
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ChEBI
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(R)-(−)-1-[4,4-bis(3-methyl-2-thienyl)-3-butenyl]nipecotic acid
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ChEBI
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(R)-tiagabine
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ChemIDplus
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115103-54-3
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CAS Registry Number
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ChemIDplus
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6375354
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Reaxys Registry Number
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Reaxys
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10530690
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PubMed citation
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Europe PMC
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22592677
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PubMed citation
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Europe PMC
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23770680
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PubMed citation
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Europe PMC
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23997364
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PubMed citation
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Europe PMC
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24440890
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PubMed citation
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Europe PMC
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24500879
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PubMed citation
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Europe PMC
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25663257
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PubMed citation
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Europe PMC
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9097364
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PubMed citation
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Europe PMC
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9449883
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PubMed citation
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Europe PMC
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