CHEBI:140271 - (7S,8,17S)-trihydroxy-(15E,19Z)-docosa-9,11,13,15,19-pentaenoic acid

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ChEBI Name (7S,8,17S)-trihydroxy-(15E,19Z)-docosa-9,11,13,15,19-pentaenoic acid
ChEBI ID CHEBI:140271
ChEBI ASCII Name (7S,8,17S)-trihydroxy-(15E,19Z)-docosa-9,11,13,15,19-pentaenoic acid
Definition A docosanoid that is (15E,19Z)-docosa-9,11,13,15,19-pentaenoic acid carrying three hydroxy substituents at positions 7S, 8 and 17S. An intermediate of specialised proresolving mediators
Stars This entity has been manually annotated by the ChEBI Team.
Submitter Bijay
Supplier Information eMolecules:539943, ZINC000004097074
Download Molfile XML SDF
Formula C22H34O5
Net Charge 0
Average Mass 378.503
Monoisotopic Mass 378.24062
InChI InChI=1S/C22H34O5/c1-2-3-9-14-19(23)15-10-6-4-5-7-11-16-20(24)21(25)17-12-8-13-18-22(26)27/h3-7,9-11,15-16,19-21,23-25H,2,8,12-14,17-18H2,1H3,(H,26,27)/b6-4?,7-5?,9-3-,15-10+,16-11?/t19-,20?,21-/m0/s1
InChIKey SWPCIZFPFUNPQW-AAZNDIRKSA-N
SMILES C(C=CC=C/C=C/[C@H](C/C=C\CC)O)=CC([C@H](CCCCCC(O)=O)O)O
Metabolite of Species Details
Homo sapiens (NCBI:txid9606) See: PubMed
Roles Classification
Chemical Role(s): Bronsted acid
A molecular entity capable of donating a hydron to an acceptor (Bronsted base).
(via oxoacid )
Biological Role(s): specialised pro-resolving mediator
A class of cell signaling molecules enzymatically derived from n-3 long chain polyunsaturated fatty acids that have important roles in orchestrating the resolution of tissue inflammation.
human xenobiotic metabolite
Any human metabolite produced by metabolism of a xenobiotic compound in humans.
Application(s): specialised pro-resolving mediator
A class of cell signaling molecules enzymatically derived from n-3 long chain polyunsaturated fatty acids that have important roles in orchestrating the resolution of tissue inflammation.
View more via ChEBI Ontology
ChEBI Ontology
Outgoing (7S,8,17S)-trihydroxy-(15E,19Z)-docosa-9,11,13,15,19-pentaenoic acid (CHEBI:140271) has role human xenobiotic metabolite (CHEBI:76967)
(7S,8,17S)-trihydroxy-(15E,19Z)-docosa-9,11,13,15,19-pentaenoic acid (CHEBI:140271) has role specialised pro-resolving mediator (CHEBI:140399)
(7S,8,17S)-trihydroxy-(15E,19Z)-docosa-9,11,13,15,19-pentaenoic acid (CHEBI:140271) is a docosanoid (CHEBI:131863)
(7S,8,17S)-trihydroxy-(15E,19Z)-docosa-9,11,13,15,19-pentaenoic acid (CHEBI:140271) is a hydroxy polyunsaturated fatty acid (CHEBI:140345)
(7S,8,17S)-trihydroxy-(15E,19Z)-docosa-9,11,13,15,19-pentaenoic acid (CHEBI:140271) is conjugate acid of (7S,8,17S)-trihydroxy-(15E,19Z)-docosa-9,11,13,15,19-pentaenoate (CHEBI:140415)
Incoming (7S,8,17S)-trihydroxy-(15E,19Z)-docosa-9,11,13,15,19-pentaenoate (CHEBI:140415) is conjugate base of (7S,8,17S)-trihydroxy-(15E,19Z)-docosa-9,11,13,15,19-pentaenoic acid (CHEBI:140271)
IUPAC Name
(7S,15E,17S,19Z)-7,8,17-trihydroxydocosa-9,11,13,15,19-pentaenoic acid
Synonyms Sources
(7S,8,17S)-trihydroxy-(9,11,13,15E,19Z)-docosapentaenoic acid ChEBI
7,8,17-trihydroxy-ω3-docosapentaenoic acid ChEBI
7,8,17-trihydroxy-omega3-docosapentaenoic acid ChEBI
resolvin D1n-3 DPA ChEBI
RvD1n-3 DPA SUBMITTER
Citations Types Sources
23736886 PubMed citation Europe PMC
28356517 PubMed citation Europe PMC
28408222 PubMed citation Europe PMC
28887458 PubMed citation Europe PMC
Last Modified
13 March 2018