CHEBI:134817 - methoxyphenamine

Main ChEBI Ontology Automatic Xrefs Reactions Pathways Models
ChEBI Name methoxyphenamine
ChEBI ID CHEBI:134817
Definition An amphetamine methylated on nitrogen and with the phenyl ring methoxylated at C-2. A β-adrenergic receptor agonist, it is used as a bronchodilator.
Stars This entity has been manually annotated by the ChEBI Team.
Supplier Information ChemicalBook:CB2512394, eMolecules:1012267
Download Molfile XML SDF
Formula C11H17NO
Net Charge 0
Average Mass 179.259
Monoisotopic Mass 179.13101
InChI InChI=1S/C11H17NO/c1-9(12-2)8-10-6-4-5-7-11(10)13-3/h4-7,9,12H,8H2,1-3H3
InChIKey OEHAYUOVELTAPG-UHFFFAOYSA-N
SMILES C1=CC=C(C(=C1)CC(NC)C)OC
Roles Classification
Chemical Role(s): Bronsted base
A molecular entity capable of accepting a hydron from a donor (Bronsted acid).
(via organic amino compound )
Biological Role(s): beta-adrenergic agonist
An agent that selectively binds to and activates beta-adrenergic receptors.
Application(s): beta-adrenergic agonist
An agent that selectively binds to and activates beta-adrenergic receptors.
bronchodilator agent
An agent that causes an increase in the expansion of a bronchus or bronchial tubes.
central nervous system stimulant
Any drug that enhances the activity of the central nervous system.
(via amphetamines )
View more via ChEBI Ontology
ChEBI Ontology
Outgoing methoxyphenamine (CHEBI:134817) has role β-adrenergic agonist (CHEBI:35522)
methoxyphenamine (CHEBI:134817) has role bronchodilator agent (CHEBI:35523)
methoxyphenamine (CHEBI:134817) is a amphetamines (CHEBI:35338)
Incoming methoxyphenamine hydrochloride (CHEBI:31830) has part methoxyphenamine (CHEBI:134817)
IUPAC Name
1-(2-methoxyphenyl)-N-methylpropan-2-amine
INNs Sources
methoxyphenamine WHO MedNet
méthoxyphénamine WHO MedNet
methoxyphenaminum WHO MedNet
metoxifenamina WHO MedNet
Synonyms Sources
2-Methoxymethamphetamine DrugCentral
methoxiphenadrin DrugCentral
methoxyphenamin DrugCentral
OMMA ChEBI
Manual Xrefs Databases
1755 DrugCentral
HMDB0041930 HMDB
View more database links
Registry Numbers Types Sources
2803353 Reaxys Registry Number Reaxys
93-30-1 CAS Registry Number DrugCentral
Citations
Thevis M, Sigmund G, Koch A, Guddat S, Maurer HH, Schänzer W (2008)
Doping control analysis of methoxyphenamine using liquid chromatography-tandem mass spectrometry.
European journal of mass spectrometry (Chichester, England) 14, 145-152 [PubMed:18708694]
[show Abstract]
Hsieh YC, Whang CW (2006)
Analysis of ethambutol and methoxyphenamine by capillary electrophoresis with electrochemiluminescence detection.
Journal of chromatography. A 1122, 279-282 [PubMed:16797572]
[show Abstract]
Coutts RT, Bolaji OO, Su P, Baker GB (1994)
Metabolism of methoxyphenamine in vitro by a CYP2D6 microsomal preparation.
Drug metabolism and disposition: the biological fate of chemicals 22, 756-760 [PubMed:7835228]
[show Abstract]
Last Modified
14 June 2018