lorcaserin hydrochloride hemihydrate (CHEBI:66852)

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ChEBI Name	lorcaserin hydrochloride hemihydrate

ChEBI ID	CHEBI:66852

Definition	A hydrate that is the hemihydrate form of lorcaserin hydrochloride. Used as an anti-obesity drug.

Stars	This entity has been manually annotated by the ChEBI Team.

Supplier Information

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Formula

C22H32Cl4N2O

Net Charge

Average Mass

482.31400

Monoisotopic Mass

480.12687

InChI

InChI=1S/2C11H14ClN.2ClH.H2O/c2*1-8-7-13-5-4-9-2-3-10(12)6-11(8)9;;;/h2*2-3,6,8,13H,4-5,7H2,1H3;2*1H;1H2/t2*8-;;;/m00.../s1

InChIKey

WRZCAWKMTLRWPR-VSODYHHCSA-N

SMILES

O.Cl.Cl.C[C@H]1CNCCc2ccc(Cl)cc12.C[C@H]1CNCCc2ccc(Cl)cc12

Roles Classification
Biological Role(s):	serotonergic agonist An agent that has an affinity for serotonin receptors and is able to mimic the effects of serotonin by stimulating the physiologic activity at the cell receptors. Serotonin agonists are used as antidepressants, anxiolytics, and in the treatment of migraine disorders.

Application(s):	appetite depressant Any agent that is used to decrease appetite. serotonergic agonist An agent that has an affinity for serotonin receptors and is able to mimic the effects of serotonin by stimulating the physiologic activity at the cell receptors. Serotonin agonists are used as antidepressants, anxiolytics, and in the treatment of migraine disorders.

ChEBI Ontology
Outgoing	lorcaserin hydrochloride hemihydrate (CHEBI:66852) has part lorcaserin hydrochloride (CHEBI:65350) lorcaserin hydrochloride hemihydrate (CHEBI:66852) has role appetite depressant (CHEBI:50507) lorcaserin hydrochloride hemihydrate (CHEBI:66852) has role serotonergic agonist (CHEBI:35941) lorcaserin hydrochloride hemihydrate (CHEBI:66852) is a hydrate (CHEBI:35505)

IUPAC Name

(1R)-8-chloro-1-methyl-2,3,4,5-tetrahydro-1H-3-benzazepine hydrochloride—water (2/1)

Synonym	Source
(1R)-8-chloro-1-methyl-2,3,4,5-tetrahydro-1H-3-benzazepine hydrochloride hemihydrate	ChEBI

Brand Name	Source
BELVIQ	ChEBI

Registry Number	Type	Source
15814539	Reaxys Registry Number	Reaxys

Last Modified

30 July 2012