CHEBI:192703 - salvigenin

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ChEBI Name salvigenin
ChEBI ID CHEBI:192703
Definition A trimethoxyflavone that is scutellarein in which the hydroxy groups at positions 4', 6, and 7 are replaced by methoxy groups.
Stars This entity has been manually annotated by the ChEBI Team.
Submitter Kristian Axelsen
Supplier Information eMolecules:29542986, ZINC000000119839
Download Molfile XML SDF
Formula C18H16O6
Net Charge 0
Average Mass 328.320
Monoisotopic Mass 328.09469
InChI InChI=1S/C18H16O6/c1-21-11-6-4-10(5-7-11)13-8-12(19)16-14(24-13)9-15(22-2)18(23-3)17(16)20/h4-9,20H,1-3H3
InChIKey QCDYOIZVELGOLZ-UHFFFAOYSA-N
SMILES COC1=CC=C(C=C1)C1=CC(=O)C2=C(O1)C=C(OC)C(OC)=C2O
Metabolite of Species Details
Astragalus brachystachys (IPNI:476523-1) See: PubMed
Teucrium flavum subsp. glaucum (NCBI:txid1046082) See: PubMed
Withania somnifera (NCBI:txid126910) See: PubMed
Hyssopus cuspidatus (NCBI:txid1439902) See: PubMed
Salvia judaica (NCBI:txid1520030) Found in aerial part (BTO:0001658). See: PubMed
Salvia atropatana (NCBI:txid1685711) Found in aerial part (BTO:0001658). See: PubMed
Salvia russellii (NCBI:txid1933755) Found in aerial part (BTO:0001658). See: PubMed
Ocimum gratissimum (NCBI:txid204144) See: PubMed
Salvia yangii (NCBI:txid268885) Found in leaf (BTO:0000713). Species also known as Perovskia atriplicifolia. See: PubMed
Achillea wilhelmsii (NCBI:txid282771) See: PubMed
Tanacetum canescens (NCBI:txid301878) Found in whole plant (BTO:0001461). See: PubMed
Ocimum basilicum (NCBI:txid39350) See: PubMed
Roles Classification
Biological Role(s): autophagy inducer
Any compound that induces the process of autophagy (the self-digestion of one or more components of a cell through the action of enzymes originating within the same cell).
apoptosis inhibitor
Any substance that inhibits the process of apoptosis (programmed cell death) in multi-celled organisms.
immunomodulator
Biologically active substance whose activity affects or plays a role in the functioning of the immune system.
plant metabolite
Any eukaryotic metabolite produced during a metabolic reaction in plants, the kingdom that include flowering plants, conifers and other gymnosperms.
Application(s): antilipemic drug
A substance used to treat hyperlipidemia (an excess of lipids in the blood).
immunomodulator
Biologically active substance whose activity affects or plays a role in the functioning of the immune system.
antineoplastic agent
A substance that inhibits or prevents the proliferation of neoplasms.
neuroprotective agent
Any compound that can be used for the treatment of neurodegenerative disorders.
hypoglycemic agent
A drug which lowers the blood glucose level.
View more via ChEBI Ontology
ChEBI Ontology
Outgoing salvigenin (CHEBI:192703) has functional parent scutellarein (CHEBI:9062)
salvigenin (CHEBI:192703) has role antilipemic drug (CHEBI:35679)
salvigenin (CHEBI:192703) has role antineoplastic agent (CHEBI:35610)
salvigenin (CHEBI:192703) has role apoptosis inhibitor (CHEBI:68494)
salvigenin (CHEBI:192703) has role autophagy inducer (CHEBI:138880)
salvigenin (CHEBI:192703) has role hypoglycemic agent (CHEBI:35526)
salvigenin (CHEBI:192703) has role immunomodulator (CHEBI:50846)
salvigenin (CHEBI:192703) has role neuroprotective agent (CHEBI:63726)
salvigenin (CHEBI:192703) has role plant metabolite (CHEBI:76924)
salvigenin (CHEBI:192703) is a monohydroxyflavone (CHEBI:38687)
salvigenin (CHEBI:192703) is a trimethoxyflavone (CHEBI:27124)
IUPAC Name
5-hydroxy-6,7-dimethoxy-2-(4-methoxyphenyl)-4H-chromen-4-one
Synonyms Sources
5-hydroxy-4',6,7-trimethoxyflavone MetaCyc
5-hydroxy-6,7,4'-trimethoxy-flavone ChemIDplus
5-hydroxy-6,7,4'-trimethoxyflavone ChemIDplus
5-hydroxy-6,7-dimethoxy-2-(4-methoxyphenyl)-4H-1-benzopyran-4-one IUPAC
7-O-methylpectolinarigenin MetaCyc
psathyrotin MetaCyc
salvigenin UniProt
Manual Xrefs Databases
C00003840 KNApSAcK
CPD-15477 MetaCyc
FDB006184 FooDB
HMDB0128577 HMDB
LMPK12111166 LIPID MAPS
View more database links
Registry Numbers Types Sources
19103-54-9 CAS Registry Number ChemIDplus
19103-54-9 CAS Registry Number NIST Chemistry WebBook
Citations Types Sources
12562087 PubMed citation Europe PMC
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Last Modified
26 August 2022