CHEBI:59594 - colesevelam

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ChEBI Name colesevelam
ChEBI ID CHEBI:59594
Definition A polyallylamine cross-linked with epichlorohydrin and alkylated with 1-bromodecane and 6-bromohexyltrimethylammonium bromide. It is used as its hydrochloride as an orally administered bile acid sequestrant to reduce the amount of cholesterol and certain fatty substances in the blood.
Stars This entity has been manually annotated by the ChEBI Team.
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Roles Classification
Application(s): anticholesteremic drug
A substance used to lower plasma cholesterol levels.
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ChEBI Ontology
Outgoing colesevelam (CHEBI:59594) has role anticholesteremic drug (CHEBI:35821)
colesevelam (CHEBI:59594) is a quaternary ammonium salt (CHEBI:35273)
colesevelam (CHEBI:59594) is a vinyl polymer macromolecule (CHEBI:53242)
Incoming colesevelam hydrochloride (CHEBI:59599) has part colesevelam (CHEBI:59594)
INN Source
colesevelam ChemIDplus
Manual Xrefs Databases
D07743 KEGG DRUG
DB00930 DrugBank
US5693675 Patent
WO9534585 Patent
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Registry Number Type Source
182815-43-6 CAS Registry Number ChemIDplus
Last Modified
02 July 2010