CHEBI:74223 - pyrrolidin-2-ones

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ChEBI Name pyrrolidin-2-ones
ChEBI ID CHEBI:74223
Definition A pyrrolidinone in which the oxo group is at position 2 of the pyrrolidine ring.
Stars This entity has been manually annotated by the ChEBI Team.
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Formula C4NOR7
Net Charge 0
Average Mass (excl. R groups) 78.04890
Monoisotopic Mass (excl. R groups) 77.99799
SMILES [*]N1C(=O)C([*])([*])C([*])([*])C1([*])[*]
ChEBI Ontology
Outgoing pyrrolidin-2-ones (CHEBI:74223) is a γ-lactam (CHEBI:74222)
pyrrolidin-2-ones (CHEBI:74223) is a pyrrolidinone (CHEBI:38275)
Incoming (−)-cotinine (CHEBI:68641) is a pyrrolidin-2-ones (CHEBI:74223)
(β-D-glucosyl)-O-mycofactocinone (CHEBI:156519) is a pyrrolidin-2-ones (CHEBI:74223)
(1E)-2-(5-chlorothiophen-2-yl)-N-{(3S)-1-[(1S)-1-methyl-2-morpholin-4-yl-2-oxoethyl]-2-oxopyrrolidin-3-yl}prop-1-ene-1-sulfonamide (CHEBI:47161) is a pyrrolidin-2-ones (CHEBI:74223)
(2R)-N-hydroxy-2-[(3S)-3-methyl-3-{4-[(2-methylquinolin-4-yl)methoxy]phenyl}-2-oxopyrrolidin-1-yl]propanamide (CHEBI:40083) is a pyrrolidin-2-ones (CHEBI:74223)
(2S)-2-[(3S)-3-{[(6-chloronaphthalen-2-yl)sulfonyl]amino}-2-oxopyrrolidin-1-yl]-N-(1-methylethyl)-N-{2-[(methylsulfonyl)amino]ethyl}propanamide (CHEBI:47440) is a pyrrolidin-2-ones (CHEBI:74223)
(2S)-N-((1S,2R)-2-hydroxy-1-(4-hydroxybenzyl)-3-{[(8S,11S)-8-[(1S)-1-methylpropyl]-7,10-dioxo-2-oxa-6,9-diazabicyclo[11.2.2]heptadeca-1(15),13,16-trien-11-yl]amino}propyl)-3-methyl-2-(2-oxopyrrolidin-1-yl)butanamide (CHEBI:44987) is a pyrrolidin-2-ones (CHEBI:74223)
(3S)-1-cyclohexyl-N-(3,5-dichlorophenyl)-5-oxopyrrolidine-3-carboxamide (CHEBI:47145) is a pyrrolidin-2-ones (CHEBI:74223)
(3S)-3-[(2S)-2-amino-3-hydroxybutyl]pyrrolidin-2-one (CHEBI:42229) is a pyrrolidin-2-ones (CHEBI:74223)
(3S)-3-[(2S)-2-amino-3-oxobutyl]pyrrolidin-2-one (CHEBI:43644) is a pyrrolidin-2-ones (CHEBI:74223)
(3S)-3-[(2S)-2-amino-4-hydroxy-3-oxobutyl]pyrrolidin-2-one (CHEBI:44618) is a pyrrolidin-2-ones (CHEBI:74223)
(3S)-N-(3-bromophenyl)-1-cyclohexyl-5-oxopyrrolidine-3-carboxamide (CHEBI:47150) is a pyrrolidin-2-ones (CHEBI:74223)
(3S)-N-(3-chloro-2-methylphenyl)-1-cyclohexyl-5-oxopyrrolidine-3-carboxamide (CHEBI:47116) is a pyrrolidin-2-ones (CHEBI:74223)
(3S)-N-(5-chloro-2-methylphenyl)-1-cyclohexyl-5-oxopyrrolidine-3-carboxamide (CHEBI:47165) is a pyrrolidin-2-ones (CHEBI:74223)
(3Z)-ravenic acid (CHEBI:66291) is a pyrrolidin-2-ones (CHEBI:74223)
(E)-2-(5-chlorothiophen-2-yl)-N-{(3S)-1-[(1S)-1-methyl-2-morpholin-4-yl-2-oxoethyl]-2-oxopyrrolidin-3-yl}ethenesulfonamide (CHEBI:47179) is a pyrrolidin-2-ones (CHEBI:74223)
1,5,5-trimethylpyrrolidin-2-one (CHEBI:43533) is a pyrrolidin-2-ones (CHEBI:74223)
1-(4-carboxy-2-guanidinophenyl)-5,5-bis(hydroxymethyl)pyrrolidin-2-one (CHEBI:45331) is a pyrrolidin-2-ones (CHEBI:74223)
1-[4-carboxy-2-(3-pentylamino)phenyl]-5,5-bis(hydroxymethyl)pyrrolidin-2-one (CHEBI:45265) is a pyrrolidin-2-ones (CHEBI:74223)
1-dodecylpyrrolidin-2-one (CHEBI:146192) is a pyrrolidin-2-ones (CHEBI:74223)
2-(3-hydroxyoctyl)-5-oxo-1-pyrrolidineheptanoic acid (CHEBI:194210) is a pyrrolidin-2-ones (CHEBI:74223)
2-(5-chlorothiophen-2-yl)-N-{(3S)-1-[(1S)-1-methyl-2-morpholin-4-yl-2-oxoethyl]-2-oxopyrrolidin-3-yl}ethanesulfonamide (CHEBI:47178) is a pyrrolidin-2-ones (CHEBI:74223)
3,3-diethyl-2-pyrrolidinone (CHEBI:180486) is a pyrrolidin-2-ones (CHEBI:74223)
3-(Dichloromethylene)-2,5-pyrrolidinedione (CHEBI:178126) is a pyrrolidin-2-ones (CHEBI:74223)
3-({[(2S)-5-oxopyrrolidin-2-yl]methyl}sulfonyl)-N-[(1S)-2,2,2-trifluoro-1-(4-fluorophenyl)ethyl]-L-alanin[N-(1-cyanocyclopropyl)]amide (CHEBI:41677) is a pyrrolidin-2-ones (CHEBI:74223)
3-amino-5-[(4-hydroxyphenyl)methyl]-4,4-dimethylpyrrolidin-2-one (CHEBI:153570) is a pyrrolidin-2-ones (CHEBI:74223)
3-fluoro-Nα-(1H-indol-2-ylcarbonyl)-N-{(2S)-1-oxo-3-[(3S)-2-oxopyrrolidin-3-yl]propan-2-yl}-L-phenylalaninamide (CHEBI:152561) is a pyrrolidin-2-ones (CHEBI:74223)
3-nitro-4-(2-oxopyrrolidin-1-yl)benzenesulfonamide (CHEBI:45603) is a pyrrolidin-2-ones (CHEBI:74223)
3-oxo-N-[(3S)-2-oxopyrrolidin-3-yl]dodecanamide (CHEBI:44612) is a pyrrolidin-2-ones (CHEBI:74223)
4-[(2R)-2-(aminomethyl)-2-(hydroxymethyl)-5-oxopyrrolidin-1-yl]-3-[(1-ethylpropyl)amino]benzoic acid (CHEBI:43250) is a pyrrolidin-2-ones (CHEBI:74223)
4-hydroxy-3-[2-oxo-3-(thieno[3,2-b]pyridine-2-sulfonylamino)pyrrolidin-1-ylmethyl]benzamidine (CHEBI:45115) is a pyrrolidin-2-ones (CHEBI:74223)
5-(5-chlorothiophen-2-yl)-N-{(3S)-1-[(1S)-1-methyl-2-morpholin-4-yl-2-oxoethyl]-2-oxopyrrolidin-3-yl}-1H-1,2,4-triazole-3-sulfonamide (CHEBI:47428) is a pyrrolidin-2-ones (CHEBI:74223)
5-[(4-hydroxyphenyl)methyl]-3-imino-4,4-dimethylpyrrolidin-2-one (CHEBI:150864) is a pyrrolidin-2-ones (CHEBI:74223)
5-chloro-N-{(3S)-1-[(1S)-1-methyl-2-morpholin-4-yl-2-oxoethyl]-2-oxopyrrolidin-3-yl}-1-benzothiophene-2-sulfonamide (CHEBI:47438) is a pyrrolidin-2-ones (CHEBI:74223)
5-chloro-N-{(3S)-1-[(1S)-1-methyl-2-morpholin-4-yl-2-oxoethyl]-2-oxopyrrolidin-3-yl}-1H-indole-2-sulfonamide (CHEBI:47442) is a pyrrolidin-2-ones (CHEBI:74223)
5-cyclohexylmethyl-2-Pyrrolidinone (CHEBI:140567) is a pyrrolidin-2-ones (CHEBI:74223)
5-oxoproline (CHEBI:16010) is a pyrrolidin-2-ones (CHEBI:74223)
5-oxopyrrolidine-2-carbaldehyde (CHEBI:44835) is a pyrrolidin-2-ones (CHEBI:74223)
5-{[(2-amino-9H-purin-6-yl)oxy]methyl}pyrrolidin-2-one (CHEBI:46424) is a pyrrolidin-2-ones (CHEBI:74223)
6-chloro-N-{(3S)-1-[(1S)-1-methyl-2-morpholin-4-yl-2-oxoethyl]-2-oxopyrrolidin-3-yl}-1-benzothiophene-2-sulfonamide (CHEBI:47439) is a pyrrolidin-2-ones (CHEBI:74223)
6-chloro-N-{(3S)-1-[(1S)-1-methyl-2-morpholin-4-yl-2-oxoethyl]-2-oxopyrrolidin-3-yl}naphthalene-2-sulfonamide (CHEBI:47441) is a pyrrolidin-2-ones (CHEBI:74223)
N-(3-acetamidopropyl)pyrrolidin-2-one (CHEBI:133185) is a pyrrolidin-2-ones (CHEBI:74223)
N-(3-furoyl)-D-valyl-L-valyl-N-((1R,2Z)-4-ethoxy-4-oxo-1-{[(3S)-2-oxopyrrolidin-3-yl]methyl}but-2-enyl)-D-leucinamide (CHEBI:40384) is a pyrrolidin-2-ones (CHEBI:74223)
N-(tert-butoxycarbonyl)-L-seryl-L-valyl-N-{(2S,3E)-5-ethoxy-5-oxo-1-[(3S)-2-oxopyrrolidin-3-yl]pent-3-en-2-yl}-L-leucinamide (CHEBI:149679) is a pyrrolidin-2-ones (CHEBI:74223)
N-[(2S)-3-cyclohexyl-1-oxo-1-({(2S)-1-oxo-3-[(3S)-2-oxopyrrolidin-3-yl]propan-2-yl}amino)propan-2-yl]-1H-indole-2-carboxamide (CHEBI:152560) is a pyrrolidin-2-ones (CHEBI:74223)
N-[(3S,6R)-6-{(S,E)-4-ethoxycarbonyl-1-[(S)-2-oxopyrrolidin-3-yl]but-3-en-2-ylcarbamoyl}-2,9-dimethyl-4-oxodec-8-en-3-yl]-5-methylisoxazole-3-carboxamide (CHEBI:41679) is a pyrrolidin-2-ones (CHEBI:74223)
N-[(5-methyl-1,2-oxazol-3-yl)carbonyl]-L-alanyl-L-valyl-N-{(2S,3E)-5-(benzyloxy)-5-oxo-1-[(3S)-2-oxopyrrolidin-3-yl]pent-3-en-2-yl}-L-leucinamide (CHEBI:39900) is a pyrrolidin-2-ones (CHEBI:74223)
N-[(5-methylisoxazol-3-yl)carbonyl]-L-alanyl-L-valyl-N1-((1S)-4-ethoxy-4-oxo-1-{[(3S)-2-oxopyrrolidin-3-yl]methyl}but-2-enyl)-L-leucinamide (CHEBI:43193) is a pyrrolidin-2-ones (CHEBI:74223)
N-[(benzyloxy)carbonyl]-O-(tert-butyl)-L-threonyl-3-cyclohexyl-N-[(1S)-2-hydroxy-1-{[(3S)-2-oxopyrrolidin-3-yl]methyl}ethyl]-L-alaninamide (CHEBI:44457) is a pyrrolidin-2-ones (CHEBI:74223)
N-methylpyrrolidin-2-one (CHEBI:7307) is a pyrrolidin-2-ones (CHEBI:74223)
N-{(3S)-1-[(1-aminoisoquinolin-7-yl)methyl]-2-oxopyrrolidin-3-yl}thieno[3,2-b]pyridine-2-sulfonamide (CHEBI:40318) is a pyrrolidin-2-ones (CHEBI:74223)
tert-butyl N-{1-[(1S)-1-{[(1R,2S)-1-(benzylcarbamoyl)-1-hydroxy-3-[(3S)-2-oxopyrrolidin-3-yl]propan-2-yl]carbamoyl}-2-cyclopropylethyl]-2-oxopyridin-3-yl}carbamate (CHEBI:147409) is a pyrrolidin-2-ones (CHEBI:74223)
trans-3-hydroxycotinine (CHEBI:71182) is a pyrrolidin-2-ones (CHEBI:74223)
trans-3-hydroxycotinine β-D-glucuronide (CHEBI:133206) is a pyrrolidin-2-ones (CHEBI:74223)
aniracetam (CHEBI:47943) is a pyrrolidin-2-ones (CHEBI:74223)
Clonostalactam (CHEBI:227154) is a pyrrolidin-2-ones (CHEBI:74223)
cotinine N-oxide (CHEBI:89087) is a pyrrolidin-2-ones (CHEBI:74223)
doxapram (CHEBI:681848) is a pyrrolidin-2-ones (CHEBI:74223)
ethyl (2E,4S)-4-[((2R)-2-{[N-(tert-butoxycarbonyl)-L-valyl]amino}-2-phenylethanoyl)amino]-5-[(3S)-2-oxopyrrolidin-3-yl]pent-2-enoate (CHEBI:42367) is a pyrrolidin-2-ones (CHEBI:74223)
ethyl (4R)-4-[((2R,5S)-2-(4-fluorobenzyl)-6-methyl-5-{[(5-methylisoxazol-3-yl)carbonyl]amino}-4-oxoheptanoyl)amino]-5-[(3S)-2-oxopyrrolidin-3-yl]pentanoate (CHEBI:40655) is a pyrrolidin-2-ones (CHEBI:74223)
Fischerellin B (CHEBI:203848) is a pyrrolidin-2-ones (CHEBI:74223)
fradafiban (CHEBI:73266) is a pyrrolidin-2-ones (CHEBI:74223)
gamma-Valerolactam (CHEBI:183240) is a pyrrolidin-2-ones (CHEBI:74223)
ivosidenib (CHEBI:145430) is a pyrrolidin-2-ones (CHEBI:74223)
lefradafiban (CHEBI:60634) is a pyrrolidin-2-ones (CHEBI:74223)
levetiracetam (CHEBI:6437) is a pyrrolidin-2-ones (CHEBI:74223)
lilaline (CHEBI:6461) is a pyrrolidin-2-ones (CHEBI:74223)
melophlin P (CHEBI:66691) is a pyrrolidin-2-ones (CHEBI:74223)
melophlin Q (CHEBI:66692) is a pyrrolidin-2-ones (CHEBI:74223)
melophlin R (CHEBI:66693) is a pyrrolidin-2-ones (CHEBI:74223)
melophlin S (CHEBI:66694) is a pyrrolidin-2-ones (CHEBI:74223)
N-Vinyl-2-pyrrolidone (CHEBI:82551) is a pyrrolidin-2-ones (CHEBI:74223)
nirmatrelvir (CHEBI:170007) is a pyrrolidin-2-ones (CHEBI:74223)
Pericoannosin C (CHEBI:209593) is a pyrrolidin-2-ones (CHEBI:74223)
Pericoannosin D (CHEBI:209599) is a pyrrolidin-2-ones (CHEBI:74223)
Pericoannosin E (CHEBI:209606) is a pyrrolidin-2-ones (CHEBI:74223)
Pericoannosin F (CHEBI:209612) is a pyrrolidin-2-ones (CHEBI:74223)
PF-00835231 (CHEBI:172918) is a pyrrolidin-2-ones (CHEBI:74223)
PF-07304814 (CHEBI:173073) is a pyrrolidin-2-ones (CHEBI:74223)
PHA-533533 (CHEBI:132239) is a pyrrolidin-2-ones (CHEBI:74223)
premycofactocin (CHEBI:150862) is a pyrrolidin-2-ones (CHEBI:74223)
Pterolactam (CHEBI:173415) is a pyrrolidin-2-ones (CHEBI:74223)
pyranonigrin I (CHEBI:133782) is a pyrrolidin-2-ones (CHEBI:74223)
pyranonigrin J (CHEBI:133781) is a pyrrolidin-2-ones (CHEBI:74223)
pyrrolidin-2-one (CHEBI:36592) is a pyrrolidin-2-ones (CHEBI:74223)
rolapitant (CHEBI:90908) is a pyrrolidin-2-ones (CHEBI:74223)
rolipram (CHEBI:104872) is a pyrrolidin-2-ones (CHEBI:74223)
Salinazinone B (CHEBI:214974) is a pyrrolidin-2-ones (CHEBI:74223)
sch 210971 (CHEBI:68748) is a pyrrolidin-2-ones (CHEBI:74223)
sch 210972 (CHEBI:68749) is a pyrrolidin-2-ones (CHEBI:74223)
sch 213766 (CHEBI:66178) is a pyrrolidin-2-ones (CHEBI:74223)
SG85 (CHEBI:147346) is a pyrrolidin-2-ones (CHEBI:74223)
Spinoxazine A (CHEBI:227351) is a pyrrolidin-2-ones (CHEBI:74223)
Spinoxazine B (CHEBI:227346) is a pyrrolidin-2-ones (CHEBI:74223)
Sulfosuccinimidyl oleate (CHEBI:183957) is a pyrrolidin-2-ones (CHEBI:74223)
tenuazonic acid (CHEBI:9440) is a pyrrolidin-2-ones (CHEBI:74223)
vibrioferrin (CHEBI:84585) is a pyrrolidin-2-ones (CHEBI:74223)
Synonyms Sources
2-pyrrolidinones ChEBI
2-pyrrolidones ChEBI
pyrrolidine-2-ones ChEBI
Last Modified
28 February 2024