InChI=1S/C44H69NO12.H2O/c1- 10- 13- 31- 19- 25(2) 18- 26(3) 20- 37(54- 8) 40- 38(55- 9) 22- 28(5) 44(52,57- 40) 41(49) 42(50) 45- 17- 12- 11- 14- 32(45) 43(51) 56- 39(29(6) 34(47) 24- 35(31) 48) 27(4) 21- 30- 15- 16- 33(46) 36(23- 30) 53- 7;/h10,19,21,26,28- 34,36- 40,46- 47,52H,1,11- 18,20,22- 24H2,2- 9H3;1H2/b25- 19+,27- 21+;/t26- ,28+,29+,30- ,31+,32- ,33+,34- ,36+,37- ,38- ,39+,40+,44+;/m0./s1 |
NWJQLQGQZSIBAF-MLAUYUEBSA-N |
O.CO[C@@H] 1C[C@@H] (CC[C@H] 1O) \C=C(/C) [C@H] 1OC(=O) [C@@H] 2CCCCN2C(=O) C(=O) [C@] 2(O) O[C@H] ([C@H] (C[C@@H] (C) C\C(C) =C\[C@@H] (CC=C) C(=O) C[C@H] (O) [C@H] 1C) OC) [C@H] (C[C@H] 2C) OC |
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immunosuppressive agent
An agent that suppresses immune function by one of several mechanisms of action. Classical cytotoxic immunosuppressants act by inhibiting DNA synthesis. Others may act through activation of T-cells or by inhibiting the activation of helper cells. In addition, an immunosuppressive agent is a role played by a compound which is exhibited by a capability to diminish the extent and/or voracity of an immune response.
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immunosuppressive agent
An agent that suppresses immune function by one of several mechanisms of action. Classical cytotoxic immunosuppressants act by inhibiting DNA synthesis. Others may act through activation of T-cells or by inhibiting the activation of helper cells. In addition, an immunosuppressive agent is a role played by a compound which is exhibited by a capability to diminish the extent and/or voracity of an immune response.
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View more via ChEBI Ontology
(3S,4R,5S,8R,9E,12S,14S,15R,16S,18R,19R,26aS)- 5,19- dihydroxy- 3- {(1E)- 1- [(1R,3R,4R)- 4- hydroxy- 3- methoxycyclohexyl]prop- 1- en- 2- yl}- 14,16- dimethoxy- 4,10,12,18- tetramethyl- 8- (prop- 2- en- 1- yl)- 5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a- hexadecahydro- 3H- 15,19- epoxypyrido[2,1- c][1,4]oxazacyclotricosine- 1,7,20,21(4H,23H)- tetrone—water (1/1)
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(−)- (3S,4R,5S,8R,9E,12S,14S,15R,16S,18R,19R,26aS)- 5,19- dihydroxy- 3- {(1E)- 1- [(1R,3R,4R)- 4- hydroxy- 3- methoxycyclohexyl]prop- 1- en- 2- yl}- 14,16- dimethoxy- 4,10,12,18- tetramethyl- 8- (prop- 2- en- 1- yl)- 5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a- hexadecahydro- 3H- 15,19- epoxypyrido[2,1- c][1,4]oxazacyclotricosine- 1,7,20,21(4H,23H)- tetrone monohydrate
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ChemIDplus
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tacrolimus
Note: (2011-01-19) Note that the name tacrolimus is used to refer both to the anhydrous form and to the monohydrate. |
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ChemIDplus
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tacrolimus monohydrate
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ChEBI
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tsukubaenolide hydrate
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ChemIDplus
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Prograf
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KEGG DRUG
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Protopic
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KEGG DRUG
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109581-93-3
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CAS Registry Number
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KEGG DRUG
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109581-93-3
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CAS Registry Number
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ChemIDplus
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6265275
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Reaxys Registry Number
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Reaxys
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