CHEBI:155927 - arterolane maleate

Main ChEBI Ontology Automatic Xrefs Reactions Pathways Models
ChEBI Name arterolane maleate
ChEBI ID CHEBI:155927
Definition The maleic acid salt of arterolane. It is an antimalarial drug used as a fixed combination with piperaquine.
Stars This entity has been manually annotated by the ChEBI Team.
Supplier Information
Download Molfile XML SDF
more structures >>
Formula C22H36N2O4.C4H4O4
Net Charge 0
Average Mass 508.612
Monoisotopic Mass 508.27847
InChI InChI=1S/C22H36N2O4.C4H4O4/c1-20(2,23)13-24-19(25)12-14-3-5-21(6-4-14)26-22(28-27-21)17-8-15-7-16(10-17)11-18(22)9-15;5-3(6)1-2-4(7)8/h14-18H,3-13,23H2,1-2H3,(H,24,25);1-2H,(H,5,6)(H,7,8)/b;2-1-/t14-,15?,16?,17?,18?,21+,22?;
InChIKey SVDSPJJUJMMDFX-CXCXETQFSA-N
SMILES C1C[C@]2(CC[C@@]1(CC(NCC(N)(C)C)=O)[H])OC3(OO2)C4CC5CC3CC(C5)C4.C(=C\C(=O)O)\C(=O)O
Roles Classification
Biological Role(s): antiplasmodial drug
An antiparasitic drug which is effective against Apicomplexan parasites in the genus Plasmodium. The genus contains over 200 species and includes those responsible for malaria.
antimalarial
A drug used in the treatment of malaria. Antimalarials are usually classified on the basis of their action against Plasmodia at different stages in their life cycle in the human.
Application(s): antiplasmodial drug
An antiparasitic drug which is effective against Apicomplexan parasites in the genus Plasmodium. The genus contains over 200 species and includes those responsible for malaria.
antimalarial
A drug used in the treatment of malaria. Antimalarials are usually classified on the basis of their action against Plasmodia at different stages in their life cycle in the human.
View more via ChEBI Ontology
ChEBI Ontology
Outgoing arterolane maleate (CHEBI:155927) has part arterolane(1+) (CHEBI:155928)
arterolane maleate (CHEBI:155927) has role antimalarial (CHEBI:38068)
arterolane maleate (CHEBI:155927) has role antiplasmodial drug (CHEBI:64915)
arterolane maleate (CHEBI:155927) is a maleate salt (CHEBI:50221)
IUPAC Name
N-(2-amino-2-methylpropyl)-2-[(1s,4s)-dispiro[cyclohexane-1,3'-[1,2,4]trioxolane-5',2''-tricyclo[3.3.1.13,7]decan]-4-yl]acetamide (2Z)-but-2-enedioate
Registry Number Type Source
959520-73-1 CAS Registry Number ChemIDplus
Citations Waiting for Citations Types Sources
21148048 PubMed citation Europe PMC
22586253 PubMed citation Europe PMC
26608469 PubMed citation Europe PMC
26818020 PubMed citation Europe PMC
26908796 PubMed citation Europe PMC
29020247 PubMed citation Europe PMC
Last Modified
26 June 2020