CHEBI:192712 - Paxlovid

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ChEBI Name Paxlovid
ChEBI ID CHEBI:192712
Definition A mixture containing nirmatrelvir and ritonavir. It is co-administered in tablet form for the treatment and post-exposure prophylaxis of COVID-19.
Stars This entity has been manually annotated by the ChEBI Team.
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Roles Classification
Biological Role(s): anticoronaviral agent
Any antiviral agent which inhibits the activity of coronaviruses.
EC 3.4.22.69 (SARS coronavirus main proteinase) inhibitor
An EC 3.4.22.* (cysteine endopeptidase) inhibitor that interferes with the action of SARS coronavirus main proteinase (EC 3.4.22.69).
HIV protease inhibitor
An inhibitor of HIV protease, an enzyme required for production of proteins needed for viral assembly.
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ChEBI Ontology
Outgoing Paxlovid (CHEBI:192712) has part nirmatrelvir (CHEBI:170007)
Paxlovid (CHEBI:192712) has part ritonavir (CHEBI:45409)
Paxlovid (CHEBI:192712) has role anticoronaviral agent (CHEBI:149553)
Paxlovid (CHEBI:192712) has role EC 3.4.22.69 (SARS coronavirus main proteinase) inhibitor (CHEBI:147285)
Paxlovid (CHEBI:192712) has role HIV protease inhibitor (CHEBI:35660)
Paxlovid (CHEBI:192712) is a mixture (CHEBI:60004)
Synonyms Sources
nirmatrelvir + ritonavir ChEBI
nirmatrelvir and ritonavir KEGG DRUG
nirmatrelvir and ritonavir mixture ChEBI
nirmatrelvir mixture with ritonavir ChEBI
nirmatrelvir plus ritonavir ChEBI
nirmatrelvir+ritonavir ChEBI
nirmatrelvir, ritonavir ChEBI
nirmatrelvir, ritonavir drug combination ChEBI
nirmatrelvir-ritonavir ChEBI
nirmatrelvir/ritonavir ChEBI
PF-07321332 and ritonavir drug combination ChEBI
PF-07321332, ritonavir ChEBI
Brand Name Source
Paxlovid KEGG DRUG
Manual Xrefs Databases
D12269 KEGG DRUG
Nirmatrelvir/ritonavir Wikipedia
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Last Modified
15 July 2022