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(1S,2R,5S)- 5- [3- (trifluoromethyl)- 5,6- dihydro[1,2,4]triazolo[4,3- a]pyrazin- 7(8H)- yl]- 2- (2,4,5- trifluorophenyl)cyclohexanamine |
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CHEBI:39959 |
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(1S,2R,5S)- 5- [3- (trifluoromethyl)- 5,6- dihydro[1,2,4]triazolo[4,3- a]pyrazin- 7(8H)- yl]- 2- (2,4,5- trifluorophenyl)cyclohexanamine |
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A triazolopyrazine that is a rigid cyclohexylamine analogue of sitagliptin. |
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![](images/goldenstar.gif) ![](images/goldenstar.gif)
This entity has been manually annotated by the ChEBI Team.
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Molfile
XML
SDF
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more structures >>
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InChI=1S/C18H19F6N5/c19- 12- 7- 14(21) 13(20) 6- 11(12) 10- 2- 1- 9(5- 15(10) 25) 28- 3- 4- 29- 16(8- 28) 26- 27- 17(29) 18(22,23) 24/h6- 7,9- 10,15H,1- 5,8,25H2/t9- ,10+,15- /m0/s1 |
CNKRZILQBKJWDS-WMFXKJRFSA-N |
[H][C@@]1(CC[C@@]([H])([C@@H](N)C1)c1cc(F)c(F)cc1F)N1CCn2c(C1)nnc2C(F)(F)F |
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View more via ChEBI Ontology
Outgoing
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(1S,2R,5S)- 5- [3- (trifluoromethyl)- 5,6- dihydro[1,2,4]triazolo[4,3- a]pyrazin- 7(8H)- yl]- 2- (2,4,5- trifluorophenyl)cyclohexanamine
(CHEBI:39959)
has functional parent
sitagliptin
(CHEBI:40237)
(1S,2R,5S)- 5- [3- (trifluoromethyl)- 5,6- dihydro[1,2,4]triazolo[4,3- a]pyrazin- 7(8H)- yl]- 2- (2,4,5- trifluorophenyl)cyclohexanamine
(CHEBI:39959)
has role
EC 3.4.* (hydrolases acting on peptide bond) inhibitor
(CHEBI:60258)
(1S,2R,5S)- 5- [3- (trifluoromethyl)- 5,6- dihydro[1,2,4]triazolo[4,3- a]pyrazin- 7(8H)- yl]- 2- (2,4,5- trifluorophenyl)cyclohexanamine
(CHEBI:39959)
is a
organofluorine compound
(CHEBI:37143)
(1S,2R,5S)- 5- [3- (trifluoromethyl)- 5,6- dihydro[1,2,4]triazolo[4,3- a]pyrazin- 7(8H)- yl]- 2- (2,4,5- trifluorophenyl)cyclohexanamine
(CHEBI:39959)
is a
triazolopyrazine
(CHEBI:48277)
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(1S,2R,5S)- 5- [3- (trifluoromethyl)- 5,6- dihydro[1,2,4]triazolo[4,3- a]pyrazin- 7(8H)- yl]- 2- (2,4,5- trifluorophenyl)cyclohexanamine
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(1S,2R,5S)- 5- [3- (TRIFLUOROMETHYL)- 5,6- DIHYDRO[1,2,4]TRIAZOLO[4,3- A]PYRAZIN- 7(8H)- YL]- 2- (2,4,5- TRIFLUOROPHENYL)CYCLOHEXANAMINE
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PDBeChem
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11103093
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Beilstein Registry Number
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Beilstein
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11103093
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Reaxys Registry Number
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Reaxys
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17433672
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PubMed citation
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Europe PMC
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