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InChI=1S/CH4O/c1-2/h2H,1H3
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ChEBI
> Main
CHEBI:7489 - neamine
Main
ChEBI Ontology
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ChEBI Name
neamine
ChEBI ID
CHEBI:7489
Definition
2-Deoxy-
D
-streptamine glycosylated at the 4-oxygen with a 6-amino-α-
D
-glucosaminyl group.
Stars
This entity has been manually annotated by the ChEBI Team.
Secondary ChEBI IDs
CHEBI:46591, CHEBI:481318
Supplier Information
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Formula
C12H26N4O6
Net Charge
0
Average Mass
322.35800
Monoisotopic Mass
322.18523
InChI
InChI=1S/C12H26N4O6/c13-
2-
5-
8(18)
9(19)
6(16)
12(21-
5)
22-
11-
4(15)
1-
3(14)
7(17)
10(11)
20/h3-
12,17-
20H,1-
2,13-
16H2/t3-
,4+,5-
,6-
,7+,8-
,9-
,10-
,11-
,12-
/m1/s1
InChIKey
SYJXFKPQNSDJLI-HKEUSBCWSA-N
SMILES
NC[C@H]1O[C@H](O[C@@H]2[C@@H](N)C[C@@H](N)[C@H](O)[C@H]2O)[C@H](N)[C@@H](O)[C@@H]1O
Roles Classification
Biological Role
(s):
antibacterial agent
A substance (or active part thereof) that kills or slows the growth of bacteria.
View more via ChEBI Ontology
ChEBI Ontology
Outgoing
neamine (
CHEBI:7489
)
has role
antibacterial agent (
CHEBI:33282
)
neamine (
CHEBI:7489
)
is a
2,6-dideoxy-α-
D
-glucoside (
CHEBI:53628
)
neamine (
CHEBI:7489
)
is a
aminoglycoside (
CHEBI:47779
)
neamine (
CHEBI:7489
)
is conjugate base of
neamine(4+) (
CHEBI:65076
)
Incoming
γ-
L
-glutamylbutirosin B (
CHEBI:65108
)
has functional parent
neamine (
CHEBI:7489
)
6'''-oxoneomycin C (
CHEBI:65098
)
has functional parent
neamine (
CHEBI:7489
)
butirosin A (
CHEBI:65112
)
has functional parent
neamine (
CHEBI:7489
)
butirosin B (
CHEBI:65110
)
has functional parent
neamine (
CHEBI:7489
)
neamine sulfate (
CHEBI:53635
)
has part
neamine (
CHEBI:7489
)
neomycin (
CHEBI:7507
)
has part
neamine (
CHEBI:7489
)
neamine(4+) (
CHEBI:65076
)
is conjugate acid of
neamine (
CHEBI:7489
)
IUPAC Name
(1
R
,2
R
,3
S
,4
R
,6
S
)-
4,6-
diamino-
2,3-
dihydroxycyclohexyl 2,6-
diamino-
2,6-
dideoxy-
α-
D
-
glucopyranoside
Synonyms
Sources
2-
desoxy-
4-
O
-
(2,6-
diamino-
2,6-
didesoxy-
α-
D
-
glucopyranosyl)-
D
-
streptamin
ChemIDplus
4-
O
-
(2,6-
diamino-
2,6-
dideoxy-
α-
D
-
glucopyranosyl)-
2-
deoxy-
D
-
streptamine
ChemIDplus
neamine
ChEMBL
Neamine
KEGG COMPOUND
Neomycin A
KEGG COMPOUND
Manual Xrefs
Databases
C01441
KEGG COMPOUND
DB04808
DrugBank
XXX
PDBeChem
View more database links
Registry Numbers
Types
Sources
26714
Reaxys Registry Number
Reaxys
3947-65-7
CAS Registry Number
KEGG COMPOUND
3947-65-7
CAS Registry Number
ChemIDplus
Citations
Types
Sources
1008820
PubMed citation
Europe PMC
16361562
PubMed citation
Europe PMC
16870442
PubMed citation
ChEMBL
16942021
PubMed citation
ChEMBL
17317190
PubMed citation
ChEMBL
17416529
PubMed citation
ChEMBL
19276260
PubMed citation
Europe PMC
20000576
PubMed citation
Europe PMC
21135992
PubMed citation
Europe PMC
Last Modified
03 July 2012