CHEBI:78711 - S. flexneri serotype 2a O-polysaccharide (O factor 9-positive)

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ChEBI Name S. flexneri serotype 2a O-polysaccharide (O factor 9-positive)
ChEBI ID CHEBI:78711
ChEBI ASCII Name S. flexneri serotype 2a O-polysaccharide (O factor 9-positive)
Definition A polysaccharide derivative comprised of a [2)-α-L-RhapIII-(1→2)-α-L-RhapII-(1→3)-α-L-RhapI-(1→3)-β-D-GlcpNAc-(1→] tetrasaccharide repeat modified by the (1→4) linkage of an α-D-glucosyl group to the RhaI residue and by addition of acetyl groups to 60% of the O-6 positions of the GlcNAc residue and to either O-3 or O-4 of many of the RhaIII residues (60% to O-3; 25% to O-4). The structure provided is representative of that in Shigella flexneri serotype 2a and shows the most common repeating unit.
Stars This entity has been manually annotated by the ChEBI Team.
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Formula (C36H57NO24)nH2O
Net Charge 0
Roles Classification
Biological Role(s): antigen
Any substance that stimulates an immune response in the body, such as through antibody production or by presentation to a T-cell receptor after binding to a major histocompability complex (MHC).
View more via ChEBI Ontology
ChEBI Ontology
Outgoing S. flexneri serotype 2a O-polysaccharide (O factor 9-positive) (CHEBI:78711) has role antigen (CHEBI:59132)
S. flexneri serotype 2a O-polysaccharide (O factor 9-positive) (CHEBI:78711) is a polysaccharide derivative (CHEBI:65212)
Synonyms Sources
[2)-α-L-RhaIII3/4Ac-(1→2)-α-L-RhaII-(1→3)-[α-D-Glc-(1→4)]-α-L-RhaI-(1→3)-β-D-Glc6,NAc2-(1→]n ChEBI
[2)-α-L-RhapIII3/4Ac-(1→2)-α-L-RhapII-(1→3)-[α-D-Glcp-(1→4)]-α-L-RhapI-(1→3)-β-D-Glcp6,NAc2-(1→]n ChEBI
Citations Waiting for Citations Types Sources
17087926 PubMed citation Europe PMC
19246033 PubMed citation Europe PMC
22724405 PubMed citation Europe PMC
24671799 PubMed citation Europe PMC
Last Modified
06 June 2014
General Comment
2014-06-06 The antigenic determinant provisionally named group O factor 9 is described in PMID:24671799.