cinanserin hydrochloride (CHEBI:147284)

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ChEBI Name	cinanserin hydrochloride

ChEBI ID	CHEBI:147284

Definition	The hydrochloride salt of cinanserin. It is an inhibitor of 3C-like proteinase of severe acute respiratory syndrome coronavirus (SARS-Cov) and reduces virus replication in vitro.

Stars	This entity has been manually annotated by the ChEBI Team.

Supplier Information

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Formula

C20H24N2OS.ClH

Net Charge

Average Mass

376.940

Monoisotopic Mass

376.13761

InChI

InChI=1S/C20H24N2OS.ClH/c1-22(2)15-8-16-24-19-12-7-6-11-18(19)21-20(23)14-13-17-9-4-3-5-10-17;/h3-7,9-14H,8,15-16H2,1-2H3,(H,21,23);1H/b14-13+;

InChIKey

LXGJPDKYMJJWRB-IERUDJENSA-N

SMILES

C=1(C=CC=CC1NC(=O)/C=C/C=2C=CC=CC2)SCCCN(C)C.Cl

Roles Classification
Biological Role(s):	antiviral agent A substance that destroys or inhibits replication of viruses. EC 3.4.22.69 (SARS coronavirus main proteinase) inhibitor An EC 3.4.22.* (cysteine endopeptidase) inhibitor that interferes with the action of SARS coronavirus main proteinase (EC 3.4.22.69). anticoronaviral agent Any antiviral agent which inhibits the activity of coronaviruses.

ChEBI Ontology
Outgoing	cinanserin hydrochloride (CHEBI:147284) has part cinanserin(1+) (CHEBI:147283) cinanserin hydrochloride (CHEBI:147284) has role anticoronaviral agent (CHEBI:149553) cinanserin hydrochloride (CHEBI:147284) has role antiviral agent (CHEBI:22587) cinanserin hydrochloride (CHEBI:147284) has role EC 3.4.22.69 (SARS coronavirus main proteinase) inhibitor (CHEBI:147285) cinanserin hydrochloride (CHEBI:147284) is a hydrochloride (CHEBI:36807)

IUPAC Name

(2E)-N-(2-{[3-(dimethylamino)propyl]sulfanyl}phenyl)-3-phenylprop-2-enamide hydrochloride

Registry Number	Type	Source
54-84-2	CAS Registry Number	ChemIDplus

Last Modified

23 April 2020