CHEBI:189865 - C75

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ChEBI Name C75
ChEBI ID CHEBI:189865
Definition A racemate comprising equimolar amount of (2R,3S)-C75 and its enantiomer, (2S,3R)-C75. It is a fatty-acid synthase (FAS) inhibitor and an activator of carnitine palmitoyl-transferase-1 that leads to weight loss and feeding inhibition in mice.
Stars This entity has been manually annotated by the ChEBI Team.
Submitter Stan Laulederkind
Roles Classification
Biological Role(s): fatty acid synthesis inhibitor
Any pathway inhibitor that inhibits the synthesis of fatty acids.
EC 2.3.1.85 (fatty acid synthase) inhibitor
An EC 2.3.1.* (acyltransferase transferring other than amino-acyl group) inhibitor that interferes with the action of fatty acid synthase (EC 2.3.1.85), a multi-enzyme protein involved in fatty acid synthesis.
apoptosis inducer
Any substance that induces the process of apoptosis (programmed cell death) in multi-celled organisms.
anti-obesity agent
Any substance which is used to reduce or control weight.
Application(s): antineoplastic agent
A substance that inhibits or prevents the proliferation of neoplasms.
View more via ChEBI Ontology
ChEBI Ontology
Outgoing C75 (CHEBI:189865) has part (2R,3S)-C75 (CHEBI:191400)
C75 (CHEBI:189865) has part (2S,3R)-C75 (CHEBI:191401)
C75 (CHEBI:189865) has role anti-obesity agent (CHEBI:74518)
C75 (CHEBI:189865) has role antineoplastic agent (CHEBI:35610)
C75 (CHEBI:189865) has role apoptosis inducer (CHEBI:68495)
C75 (CHEBI:189865) has role EC 2.3.1.85 (fatty acid synthase) inhibitor (CHEBI:71476)
C75 (CHEBI:189865) has role fatty acid synthesis inhibitor (CHEBI:50185)
C75 (CHEBI:189865) is a racemate (CHEBI:60911)
IUPAC Name
rac-(2R,3S)-4-methylidene-2-octyl-5-oxotetrahydrofuran-3-carboxylic acid
Synonyms Sources
(±)-C75 SUBMITTER
(2R*,3S*)-4-methylidene-2-octyl-5-oxotetrahydrofuran-3-carboxylic acid ChEBI
(2R*,3S*)-tetrahydro-4-methylene-2-octyl-5-oxo-3-furancarboxylic acid ChEBI
C75 (racemic mixture of trans-isomers) ChEBI
C75 trans SUBMITTER
trans-C 75 ChemIDplus
trans-C75 SUBMITTER
trans-tetrahydro-4-methylene-2-octyl-5-oxo-3-furancarboxylic acid ChEBI
Registry Number Type Source
191282-48-1 CAS Registry Number ChemIDplus
Citations Waiting for Citations Types Sources
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Last Modified
12 May 2022