alpha-Hydroxyalprazolam (CHEBI:192657)

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This entity has been annotated by a third party. If you would like more information added to this entry, please contact ChEBI via email or GitHub.

ChEBI Name	alpha-Hydroxyalprazolam

ChEBI ID	CHEBI:192657

Stars	This entity has been manually annotated by a third party.

Submitter	MetaboLights

Supplier Information

Download	Molfile XML SDF

Formula

C17H13ClN4O

Net Charge

Average Mass

324.770

Monoisotopic Mass

324.07779

InChI

InChI=1S/C17H13ClN4O/c18-12-6-7-14-13(8-12)17(11-4-2-1-3-5-11)19-9-15-20-21-16(10-23)22(14)15/h1-8,23H,9-10H2

InChIKey

ZURUZYHEEMDQBU-UHFFFAOYSA-N

SMILES

ClC1=CC2=C(N3C(=NN=C3CO)CN=C2C4=CC=CC=C4)C=C1

Metabolite of Species	Details
Valsa sordida (NCBI:txid252740)	Found in Whole Organism (NCIT:C13413). See: MetaboLights Study

Roles Classification
Biological Role(s):	GABA modulator A substance that does not act as agonist or antagonist but does affect the gamma-aminobutyric acid receptor-ionophore complex. GABA-A receptors appear to have at least three allosteric sites at which modulators act: a site at which benzodiazepines act by increasing the opening frequency of gamma-aminobutyric acid-activated chloride channels; a site at which barbiturates act to prolong the duration of channel opening; and a site at which some steroids may act. (via benzodiazepine )

Application(s):	GABA modulator A substance that does not act as agonist or antagonist but does affect the gamma-aminobutyric acid receptor-ionophore complex. GABA-A receptors appear to have at least three allosteric sites at which modulators act: a site at which benzodiazepines act by increasing the opening frequency of gamma-aminobutyric acid-activated chloride channels; a site at which barbiturates act to prolong the duration of channel opening; and a site at which some steroids may act. (via benzodiazepine )

ChEBI Ontology
Outgoing	alpha-Hydroxyalprazolam (CHEBI:192657) is a triazolobenzodiazepine (CHEBI:35501)

IUPAC Name

(8-chloro-6-phenyl-4H-[1,2,4]triazolo[4,3-a][1,4]benzodiazepin-1-yl)methanol

Registry Number	Type	Source
37115-43-8	CAS Registry Number	ChemIDplus