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α-melanocyte stimulating hormone |
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CHEBI:195325 |
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alpha-melanocyte stimulating hormone |
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A thirteen amino acid peptide hormone consisting of N-acetyl-L-Ser, L-Tyr, L-Ser, L-Met, L-Glu, L-His, L-Phe, L-Arg, L-Trp, Gly, L-Lys, L-Pro and L-valinamide units joined in sequence by peptide linkages. It is an endogenous melanocortin receptor agonist that exhibits anti-inflammatory activity. |
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This entity has been manually annotated by the ChEBI Team.
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Wei-Chia Tseng
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Molfile
XML
SDF
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InChI=1S/C77H109N21O19S/c1-42(2)64(65(79)106)97-75(116)61-20-13-30-98(61)76(117)54(18-10-11-28-78)88-62(103)38-85-66(107)57(34-46-36-84-50-17-9-8-16-49(46)50)94-67(108)51(19-12-29-83-77(80)81)89-70(111)55(32-44-14-6-5-7-15-44)92-72(113)58(35-47-37-82-41-86-47)95-68(109)52(25-26-63(104)105)90-69(110)53(27-31-118-4)91-74(115)60(40-100)96-71(112)56(33-45-21-23-48(102)24-22-45)93-73(114)59(39-99)87-43(3)101/h5-9,14-17,21-24,36-37,41-42,51-61,64,84,99-100,102H,10-13,18-20,25-35,38-40,78H2,1-4H3,(H2,79,106)(H,82,86)(H,85,107)(H,87,101)(H,88,103)(H,89,111)(H,90,110)(H,91,115)(H,92,113)(H,93,114)(H,94,108)(H,95,109)(H,96,112)(H,97,116)(H,104,105)(H4,80,81,83)/t51-,52-,53-,54-,55-,56-,57-,58-,59-,60-,61-,64-/m0/s1 |
WHNFPRLDDSXQCL-UAZQEYIDSA-N |
CSCC[C@H](NC(=O)[C@H](CO)NC(=O)[C@H](CC1=CC=C(O)C=C1)NC(=O)[C@H](CO)NC(C)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC1=CNC=N1)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC1=CNC2=C1C=CC=C2)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C(C)C)C(N)=O |
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Bronsted base
A molecular entity capable of accepting a hydron from a donor (Bronsted acid).
(via organic amino compound )
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hormone
Originally referring to an endogenous compound that is formed in specialized organ or group of cells and carried to another organ or group of cells, in the same organism, upon which it has a specific regulatory function, the term is now commonly used to include non-endogenous, semi-synthetic and fully synthetic analogues of such compounds.
(via peptide hormone )
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anti-inflammatory agent
Any compound that has anti-inflammatory effects.
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View more via ChEBI Ontology
N-acetyl-L-seryl-L-tyrosyl-L-seryl-L-methionyl-L-α-glutamyl-L-histidyl-L-phenylalanyl-L-arginyl-L-tryptophylglycyl-L-lysyl-L-prolyl-L-valinamide
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Ac-L-Ser-L-Tyr-L-Ser-L-Met-L-Glu-L-His-L-Phe-L-Arg-L-Trp-Gly-L-Lys-L-Pro-L-Val-NH2
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ChEBI
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Ac-Ser-Tyr-Ser-Met-Glu-His-Phe-Arg-Trp-Gly-Lys-Pro-Val-NH2
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ChEBI
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α-intermedin
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ChEBI
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α-melanotropin
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ChEBI
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α-MSH
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ChEBI
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intermedin
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SUBMITTER
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melanotropin
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SUBMITTER
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melanotropin α
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SUBMITTER
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N-Ac-L-Ser-L-Tyr-L-Ser-L-Met-L-Glu-L-His-L-Phe-L-Arg-L-Trp-Gly-L-Lys-L-Pro-L-Val-NH2
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ChEBI
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N-acetyl-L-Ser-L-Tyr-L-Ser-L-Met-L-α-Glu-L-His-L-Phe-L-Arg-L-Trp-Gly-L-Lys-L-Pro-L-valinamide
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ChEBI
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581-05-5
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CAS Registry Number
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ChEBI
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741840
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Reaxys Registry Number
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Reaxys
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33210000
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PubMed citation
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Europe PMC
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33523420
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PubMed citation
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Europe PMC
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33639356
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PubMed citation
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Europe PMC
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33765043
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PubMed citation
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Europe PMC
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34904527
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PubMed citation
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Europe PMC
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35717488
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PubMed citation
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Europe PMC
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35733058
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PubMed citation
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Europe PMC
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36900442
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PubMed citation
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Europe PMC
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37001274
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PubMed citation
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Europe PMC
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37217094
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PubMed citation
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Europe PMC
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