| N-methyl-D-aspartic acid or N-methyl-D-aspartate (NMDA) is an amino acid derivative that acts as a specific agonist at the NMDA receptor mimicking the action of glutamate, the neurotransmitter which normally acts at that receptor. Unlike glutamate, NMDA only binds to and regulates the NMDA receptor and has no effect on other glutamate receptors (such as those for AMPA and kainate). NMDA receptors are particularly important when they become overactive during, for example, withdrawal from alcohol as this causes symptoms such as agitation and, sometimes, epileptiform seizures.
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Read full article at Wikipedia
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| InChI=1S/C5H9NO4/c1-6-3(5(9)10)2-4(7)8/h3,6H,2H2,1H3,(H,7,8)(H,9,10)/t3-/m1/s1 |
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Bronsted base
A molecular entity capable of accepting a hydron from a donor (Bronsted acid).
(via organic amino compound )
Bronsted acid
A molecular entity capable of donating a hydron to an acceptor (Bronsted base).
(via oxoacid )
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neurotransmitter agent
A substance used for its pharmacological action on any aspect of neurotransmitter systems. Neurotransmitter agents include agonists, antagonists, degradation inhibitors, uptake inhibitors, depleters, precursors, and modulators of receptor function.
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neurotransmitter agent
A substance used for its pharmacological action on any aspect of neurotransmitter systems. Neurotransmitter agents include agonists, antagonists, degradation inhibitors, uptake inhibitors, depleters, precursors, and modulators of receptor function.
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View more via ChEBI Ontology
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(R)-2-Methylamino-succinic acid
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ChEMBL
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2-Methylamino-succinic acid
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ChEMBL
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Methyl aspartic acid
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ChemIDplus
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N-Methyl aspartic acid
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ChemIDplus
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N-Methyl-D-aspartate
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KEGG COMPOUND
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N-Methyl-D-aspartic acid
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KEGG COMPOUND
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N-Methylaspartate
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ChemIDplus
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NMDA
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KEGG COMPOUND
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1724431
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Reaxys Registry Number
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Reaxys
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6384-92-5
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CAS Registry Number
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ChemIDplus
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