CHEBI:32232 - tiquizium bromide

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ChEBI Name tiquizium bromide
ChEBI ID CHEBI:32232
Definition A organic bromide salt of tiquizium. It is an antispasmodic drug used for the treatment of convulsion and hypermobility in gastritis, gastric ulcer, duodenal ulcer, enteritis, irritable bowel syndrome, gallbladder disease, biliary tract disease and urolithiasis.
Stars This entity has been manually annotated by the ChEBI Team.
Supplier Information
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Formula C19H24NS2.Br
Net Charge 0
Average Mass 410.430
Monoisotopic Mass 409.05336
InChI InChI=1S/C19H24NS2.BrH/c1-20-11-3-2-6-16(20)10-9-15(14-20)19(17-7-4-12-21-17)18-8-5-13-22-18;/h4-5,7-8,12-13,16H,2-3,6,9-11,14H2,1H3;1H/q+1;/p-1/t16-,20-;/m1./s1
InChIKey VKBNGRDAHSELMQ-KYSFMIDTSA-M
SMILES C(=C1C[N@+]2(C)[C@@](CC1)(CCCC2)[H])(C3=CC=CS3)C4=CC=CS4.[Br-]
Roles Classification
Biological Role(s): muscarinic antagonist
A drug that binds to but does not activate muscarinic cholinergic receptors, thereby blocking the actions of endogenous acetylcholine or exogenous agonists.
Application(s): muscarinic antagonist
A drug that binds to but does not activate muscarinic cholinergic receptors, thereby blocking the actions of endogenous acetylcholine or exogenous agonists.
antispasmodic drug
A drug that suppresses spasms. These are usually caused by smooth muscle contraction, especially in tubular organs. The effect is to prevent spasms of the stomach, intestine or urinary bladder.
anti-ulcer drug
One of various classes of drugs with different action mechanisms used to treat or ameliorate peptic ulcer or irritation of the gastrointestinal tract.
View more via ChEBI Ontology
ChEBI Ontology
Outgoing tiquizium bromide (CHEBI:32232) has part tiquizium (CHEBI:145714)
tiquizium bromide (CHEBI:32232) has role anti-ulcer drug (CHEBI:49201)
tiquizium bromide (CHEBI:32232) has role antispasmodic drug (CHEBI:53784)
tiquizium bromide (CHEBI:32232) has role muscarinic antagonist (CHEBI:48876)
tiquizium bromide (CHEBI:32232) is a organic bromide salt (CHEBI:48369)
tiquizium bromide (CHEBI:32232) is a quaternary ammonium salt (CHEBI:35273)
IUPAC Name
(5R,9aR)-3-[di(thiophen-2-yl)methylidene]-5-methyloctahydro-2H-quinolizinium bromide
INNs Sources
bromure de tiquizium WHO MedNet
bromuro de tiquizio WHO MedNet
tiquizii bromidum WHO MedNet
tiquizium bromide WHO MedNet
Synonyms Sources
(5R,9aR)-3-[di(thiophen-2-yl)methylidene]-5-methyloctahydro-2H-quinolizin-5-ium bromide IUPAC
3-(di(2-thienyl)methylene)-5-methyldecahydroquinolizinium bromide ChemIDplus
3-(di-2-thienylmethylene)-5-methyl-trans-quinolizidinium bromide ChEBI
HSR 902 ChEBI
HSR-902 ChemIDplus
trans-3-(di-2-thienylmethylene)octahydro-5-methyl-2H-quinolizinium bromide ChemIDplus
Brand Names Sources
Advaston ChEBI
Aspora ChEBI
Breiful ChEBI
Gastirol ChEBI
Thiameron ChEBI
Thiaton KEGG DRUG
Thiwan ChEBI
Tiapaston ChEBI
Manual Xrefs Databases
2678 DrugCentral
D01875 KEGG DRUG
View more database links
Registry Number Type Source
71731-58-3 CAS Registry Number ChemIDplus
Citations Waiting for Citations Types Sources
10475017 PubMed citation Europe PMC
11855677 PubMed citation Europe PMC
2881461 PubMed citation Europe PMC
2895053 PubMed citation Europe PMC
2895054 PubMed citation Europe PMC
3656779 PubMed citation Europe PMC
4090525 PubMed citation Europe PMC
6120131 PubMed citation Europe PMC
6277751 PubMed citation Europe PMC
6631675 PubMed citation Europe PMC
6677720 PubMed citation Europe PMC
7262709 PubMed citation Europe PMC
7302972 PubMed citation Europe PMC
8839659 PubMed citation Europe PMC
Last Modified
20 December 2019