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Examples:
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,
InChI=1S/CH4O/c1-2/h2H,1H3
,
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ChEBI
> Main
CHEBI:50123 - (+)-rosiglitazone
Main
ChEBI Ontology
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ChEBI Name
(+)-rosiglitazone
ChEBI ID
CHEBI:50123
Stars
This entity has been manually annotated by the ChEBI Team.
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Formula
C18H19N3O3S
Net Charge
0
Average Mass
357.42700
Monoisotopic Mass
357.11471
InChI
InChI=1S/C18H19N3O3S/c1-
21(16-
4-
2-
3-
9-
19-
16)
10-
11-
24-
14-
7-
5-
13(6-
8-
14)
12-
15-
17(22)
20-
18(23)
25-
15/h2-
9,15H,10-
12H2,1H3,(H,20,22,23)
/t15-
/m1/s1
InChIKey
YASAKCUCGLMORW-OAHLLOKOSA-N
SMILES
CN(CCOc1ccc(C[C@H]2SC(=O)NC2=O)cc1)c1ccccn1
Roles Classification
Chemical Role
(s):
Bronsted base
A molecular entity capable of accepting a hydron from a donor (Br
o
nsted acid).
(via
organic amino compound
)
Biological Role
(s):
insulin-sensitizing drug
An agent which overcomes insulin resistance by activation of the peroxisome proliferator activated receptor gamma (PPAR-gamma).
(via
rosiglitazone
)
ferroptosis inhibitor
Any substance that inhibits the process of ferroptosis (a type of programmed cell death dependent on iron and characterized by the accumulation of lipid peroxides) in organisms.
(via
rosiglitazone
)
EC 6.2.1.3 (long-chain-fatty-acid--CoA ligase) inhibitor
An EC 6.2.1.* (acid-thiol ligase) inhibitor that interferes with the action of a long-chain-fatty-acid
CoA ligase (EC 6.2.1.3).
(via
rosiglitazone
)
Application
(s):
insulin-sensitizing drug
An agent which overcomes insulin resistance by activation of the peroxisome proliferator activated receptor gamma (PPAR-gamma).
(via
rosiglitazone
)
View more via ChEBI Ontology
ChEBI Ontology
Outgoing
(+)-rosiglitazone (
CHEBI:50123
)
is a
rosiglitazone (
CHEBI:50122
)
(+)-rosiglitazone (
CHEBI:50123
)
is enantiomer of
(−)-rosiglitazone (
CHEBI:50125
)
Incoming
(−)-rosiglitazone (
CHEBI:50125
)
is enantiomer of
(+)-rosiglitazone (
CHEBI:50123
)
IUPAC Name
(5
R
)-5-(4-{2-[methyl(pyridin-2-yl)amino]ethoxy}benzyl)-1,3-thiazolidine-2,4-dione
Manual Xref
Database
DB00412
DrugBank
View more database links
Registry Number
Type
Source
7082203
Beilstein Registry Number
Beilstein
Last Modified
17 October 2009