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ChEBI
> Main
CHEBI:53783 - alosetron hydrochloride
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ChEBI Name
alosetron hydrochloride
ChEBI ID
CHEBI:53783
Definition
The hydrochloride salt of alosetron.
Stars
This entity has been manually annotated by the ChEBI Team.
Supplier Information
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Molfile
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Molfile
Formulae
C17H18N4O.HCl
C17H19ClN4O
Net Charge
0
Average Mass
330.81200
Monoisotopic Mass
330.12474
InChI
InChI=1S/C17H18N4O.ClH/c1-
11-
13(19-
10-
18-
11)
9-
21-
8-
7-
15-
16(17(21)
22)
12-
5-
3-
4-
6-
14(12)
20(15)
2;/h3-
6,10H,7-
9H2,1-
2H3,(H,18,19)
;1H
InChIKey
FNYQZOVOVDSGJH-UHFFFAOYSA-N
SMILES
[H+].[Cl-].Cc1[nH]cnc1CN1CCc2c(C1=O)c1ccccc1n2C
Roles Classification
Biological Role
(s):
serotonergic antagonist
Drugs that bind to but do not activate serotonin receptors, thereby blocking the actions of serotonin or serotonergic agonists.
Application
(s):
antiemetic
A drug used to prevent nausea or vomiting. An antiemetic may act by a wide range of mechanisms: it might affect the medullary control centres (the vomiting centre and the chemoreceptive trigger zone) or affect the peripheral receptors.
serotonergic antagonist
Drugs that bind to but do not activate serotonin receptors, thereby blocking the actions of serotonin or serotonergic agonists.
View more via ChEBI Ontology
ChEBI Ontology
Outgoing
alosetron hydrochloride (
CHEBI:53783
)
has part
alosetron (
CHEBI:253342
)
alosetron hydrochloride (
CHEBI:53783
)
has role
antiemetic (
CHEBI:50919
)
alosetron hydrochloride (
CHEBI:53783
)
has role
serotonergic antagonist (
CHEBI:48279
)
alosetron hydrochloride (
CHEBI:53783
)
is a
hydrochloride (
CHEBI:36807
)
IUPAC Name
5-
methyl-
2-
[(5-
methyl-
1
H
-
imidazol-
4-
yl)methyl]-
2,3,4,5-
tetrahydro-
1
H
-
pyrido[4,3-
b
]indol-
1-
one hydrochloride
INN
Source
alosetron
ChEBI
Synonyms
Sources
2,3,4,5-
Tetrahydro-
5-
methyl-
2-
((5-
methylimidazol-
4-
yl)methyl)-
1H-
pyrido(4,3-
b)indol-
1-
one monohydrochloride
ChemIDplus
Alosetron HCl
DrugBank
Manual Xrefs
Databases
D02829
KEGG DRUG
DB00969
DrugBank
View more database links
Registry Numbers
Types
Sources
122852-69-1
CAS Registry Number
ChemIDplus
122852-69-1
CAS Registry Number
KEGG DRUG
8455746
Beilstein Registry Number
Beilstein
Last Modified
13 June 2014