Tetracycline, sold under various brand names, is an antibiotic in the tetracyclines family of medications, used to treat a number of infections, including acne, cholera, brucellosis, plague, malaria, and syphilis. It is available in oral and topical formulations.
Common side effects include vomiting, diarrhea, rash, and loss of appetite. Other side effects include poor tooth development if used by children less than eight years of age, kidney problems, and sunburning easily. Use during pregnancy may harm the baby. It works by inhibiting protein synthesis in bacteria.
Tetracycline was patented in 1953 and was approved for prescription use in 1954. It is on the World Health Organization's List of Essential Medicines. Tetracycline is available as a generic medication. Tetracycline was originally made from bacteria of the genus Streptomyces. |
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human metabolite
Any mammalian metabolite produced during a metabolic reaction in humans (Homo sapiens).
(via 5,6,7,8-tetrahydrobiopterin )
cofactor
An organic molecule or ion (usually a metal ion) that is required by an enzyme for its activity. It may be attached either loosely (coenzyme) or tightly (prosthetic group).
coenzyme
A low-molecular-weight, non-protein organic compound participating in enzymatic reactions as dissociable acceptor or donor of chemical groups or electrons.
(via 5,6,7,8-tetrahydrobiopterin )
prosthetic group
A tightly bound, specific nonpolypeptide unit in a protein determining and involved in its biological activity.
(via 5,6,7,8-tetrahydrobiopterin )
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diagnostic agent
A substance administered to aid diagnosis of a disease.
nutraceutical
A product in capsule, tablet or liquid form that provide essential nutrients, such as a vitamin, an essential mineral, a protein, an herb, or similar nutritional substance.
(via 5,6,7,8-tetrahydrobiopterin )
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View more via ChEBI Ontology
(6R)-2-amino-6-[(1R,2S)-1,2-dihydroxypropyl]-5,6,7,8-tetrahydropteridin-4(3H)-one
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sapropterin
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ChemIDplus
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sapropterina
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ChemIDplus
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sapropterinum
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ChemIDplus
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(−)-(6R)-2-amino-6-((1R,2S)-1,2-dihydroxypropyl)-5,6,7,8-tetrahydro-4(3H)-pteridinone
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ChemIDplus
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(6R)-L-erythro-5,6,7,8-tetrahydrobiopterin
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UniProt
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(6R)-L-erythro-tetrahydrobiopterin
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ChEBI
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2-Amino-6-(1,2-dihydroxypropyl)-5,6,7,8-tetrahydoro-4(1H)-pteridinone
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KEGG COMPOUND
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5,6,7,8-Tetrahydrobiopterin
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KEGG COMPOUND
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6R-5,6,7,8-tetrahydrobiopterin
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ChemIDplus
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6R-BH4
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ChEBI
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6R-L-5,6,7,8-tetrahydrobiopterin
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ChemIDplus
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R-THBP
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ChEBI
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tetrahydrobiopterin
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DrugBank
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2612
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DrugCentral
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C00018229
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KNApSAcK
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C00272
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KEGG COMPOUND
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CPD-14053
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MetaCyc
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D08505
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KEGG DRUG
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DB00360
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DrugBank
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EP191335
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Patent
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H4B
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PDBeChem
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HMDB0000787
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HMDB
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Sapropterin
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Wikipedia
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US4713454
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Patent
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View more database links |
17528-72-2
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CAS Registry Number
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KEGG COMPOUND
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27070-47-9
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CAS Registry Number
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ChemIDplus
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4699705
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Reaxys Registry Number
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Reaxys
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