CHEBI:66392 - millewanin H

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ChEBI Name millewanin H
ChEBI ID CHEBI:66392
Definition A hydroxyisoflavone that is isoflavone substituted by hydroxy groups at positions 5, 7, 3' and 4', a prenyl group at position 6 and a 2-hydroxy-3-methylbut-3-enyl moiety at position 8. Isolated from the leaves of Millettia pachycarpa, it exhibits antiestrogenic activity.
Stars This entity has been manually annotated by the ChEBI Team.
Supplier Information
Download Molfile XML SDF
Formula C25H26O7
Net Charge 0
Average Mass 438.46970
Monoisotopic Mass 438.16785
InChI InChI=1S/C25H26O7/c1-12(2)5-7-15-22(29)16(10-19(27)13(3)4)25-21(23(15)30)24(31)17(11-32-25)14-6-8-18(26)20(28)9-14/h5-6,8-9,11,19,26-30H,3,7,10H2,1-2,4H3
InChIKey RZHIZFURFGRHHQ-UHFFFAOYSA-N
SMILES CC(C)=CCc1c(O)c(CC(O)C(C)=C)c2occ(-c3ccc(O)c(O)c3)c(=O)c2c1O
Metabolite of Species Details
Millettia pachycarpa (NCBI:txid690557) Found in leaf (BTO:0000713). 10:11 Enantiomeric mixture See: PubMed
Roles Classification
Biological Role(s): metabolite
Any intermediate or product resulting from metabolism. The term 'metabolite' subsumes the classes commonly known as primary and secondary metabolites.
Application(s): anti-estrogen
A drug which acts to reduce estrogenic activity in the body, either by reducing the amount of estrogen or by reducing the activity of whatever estrogen is present.
View more via ChEBI Ontology
ChEBI Ontology
Outgoing millewanin H (CHEBI:66392) has role anti-estrogen (CHEBI:50751)
millewanin H (CHEBI:66392) has role metabolite (CHEBI:25212)
millewanin H (CHEBI:66392) is a hydroxyisoflavone (CHEBI:38755)
millewanin H (CHEBI:66392) is a secondary alcohol (CHEBI:35681)
IUPAC Name
3-(3,4-dihydroxyphenyl)-5,7-dihydroxy-8-(2-hydroxy-3-methylbut-3-en-1-yl)-6-(3-methylbut-2-en-1-yl)-4H-chromen-4-one
Registry Number Type Source
18586901 Reaxys Registry Number Reaxys
Citation Waiting for Citations Type Source
16441086 PubMed citation Europe PMC
Last Modified
10 April 2013
General Comment
2013-04-10 The compound was isolated as an enantiomeric mixture.