NF-κB inhibitor |
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CHEBI:73240 |
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NF-kappaB inhibitor |
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An inhibitor of NF-κB (nuclear factor κ-light-chain-enhancer of activated B cells), a protein complex involved in the transcription of DNA. |
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This entity has been manually annotated by the ChEBI Team.
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Nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB) is a family of transcription factor protein complexes that controls transcription of DNA, cytokine production and cell survival. NF-κB is found in almost all animal cell types and is involved in cellular responses to stimuli such as stress, cytokines, free radicals, heavy metals, ultraviolet irradiation, oxidized LDL, and bacterial or viral antigens. NF-κB plays a key role in regulating the immune response to infection. Incorrect regulation of NF-κB has been linked to cancer, inflammatory and autoimmune diseases, septic shock, viral infection, and improper immune development. NF-κB has also been implicated in processes of synaptic plasticity and memory. |
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NF-kappaB inhibitor
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ChEBI
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NF-kappaB inhibitors
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ChEBI
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NF-κB inhibitors
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ChEBI
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NF-kB inhibitor
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ChEBI
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NF-kB inhibitors
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ChEBI
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Nuclear factor kappa B inhibitor
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ChEBI
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Nuclear factor kappa B inhibitors
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ChEBI
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nuclear factor κ-light-chain-enhancer of activated B cells inhibitor
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ChEBI
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nuclear factor κ-light-chain-enhancer of activated B cells inhibitors
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ChEBI
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