propafenone hydrochloride (CHEBI:8466)

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ChEBI Name	propafenone hydrochloride

ChEBI ID	CHEBI:8466

Definition	A hydrochloride that is the monohydrochloride salt of propafenone. It is a class 1C antiarrhythmic drug with local anesthetic effects, and is used in the management of supraventricular and ventricular arrhythmias.

Stars	This entity has been manually annotated by the ChEBI Team.

Supplier Information

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Formulae

C21H27NO3.HCl
C21H28ClNO3

Net Charge

Average Mass

377.90500

Monoisotopic Mass

377.17577

InChI

InChI=1S/C21H27NO3.ClH/c1-2-14-22-15-18(23)16-25-21-11-7-6-10-19(21)20(24)13-12-17-8-4-3-5-9-17;/h3-11,18,22-23H,2,12-16H2,1H3;1H

InChIKey

XWIHRGFIPXWGEF-UHFFFAOYSA-N

SMILES

Cl.CCCNCC(O)COc1ccccc1C(=O)CCc1ccccc1

Roles Classification
Application(s):	anti-arrhythmia drug A drug used for the treatment or prevention of cardiac arrhythmias. Anti-arrhythmia drugs may affect the polarisation-repolarisation phase of the action potential, its excitability or refractoriness, or impulse conduction or membrane responsiveness within cardiac fibres.

ChEBI Ontology
Outgoing	propafenone hydrochloride (CHEBI:8466) has part propafenone(1+) (CHEBI:63650) propafenone hydrochloride (CHEBI:8466) has role anti-arrhythmia drug (CHEBI:38070) propafenone hydrochloride (CHEBI:8466) is a hydrochloride (CHEBI:36807)

IUPAC Name

1-{2-[2-hydroxy-3-(propylamino)propoxy]phenyl}-3-phenylpropan-1-one hydrochloride

Synonyms	Sources
2-hydroxy-3-[2-(3-phenylpropanoyl)phenoxy]-N-propylpropan-1-aminium chloride	IUPAC
Propafenon hydrochlorid	ChemIDplus
propafenone HCl	ChemIDplus

Last Modified

19 January 2012