CHEBI:8736 - (R)-(+)-propranolol

Main ChEBI Ontology Automatic Xrefs Reactions Pathways Models
ChEBI Name (R)-(+)-propranolol
ChEBI ID CHEBI:8736
ChEBI ASCII Name (R)-(+)-propranolol
Stars This entity has been manually annotated by the ChEBI Team.
Supplier Information
Download Molfile XML SDF
Formula C16H21NO2
Net Charge 0
Average Mass 259.34340
Monoisotopic Mass 259.15723
InChI InChI=1S/C16H21NO2/c1-12(2)17-10-14(18)11-19-16-9-5-7-13-6-3-4-8-15(13)16/h3-9,12,14,17-18H,10-11H2,1-2H3/t14-/m1/s1
InChIKey AQHHHDLHHXJYJD-CQSZACIVSA-N
SMILES CC(C)NC[C@@H](O)COc1cccc2ccccc12
Roles Classification
Chemical Role(s): environmental contaminant
Any minor or unwanted substance introduced into the environment that can have undesired effects.
(via propranolol )
Bronsted base
A molecular entity capable of accepting a hydron from a donor (Bronsted acid).
(via organic amino compound )
Biological Role(s): human blood serum metabolite
Any metabolite (endogenous or exogenous) found in human blood serum samples.
(via propranolol )
xenobiotic
A xenobiotic (Greek, xenos "foreign"; bios "life") is a compound that is foreign to a living organism. Principal xenobiotics include: drugs, carcinogens and various compounds that have been introduced into the environment by artificial means.
(via propranolol )
beta-adrenergic antagonist
An agent that binds to but does not activate beta-adrenergic receptors thereby blocking the actions of endogenous or exogenous beta-adrenergic agonists. beta-Adrenergic antagonists are used for treatment of hypertension, cardiac arrhythmias, angina pectoris, glaucoma, migraine headaches and anxiety.
(via propranolol )
Application(s): antihypertensive agent
Any drug used in the treatment of acute or chronic vascular hypertension regardless of pharmacological mechanism.
(via propranolol )
beta-adrenergic antagonist
An agent that binds to but does not activate beta-adrenergic receptors thereby blocking the actions of endogenous or exogenous beta-adrenergic agonists. beta-Adrenergic antagonists are used for treatment of hypertension, cardiac arrhythmias, angina pectoris, glaucoma, migraine headaches and anxiety.
(via propranolol )
anxiolytic drug
Anxiolytic drugs are agents that alleviate anxiety, tension, and anxiety disorders, promote sedation, and have a calming effect without affecting clarity of consciousness or neurologic conditions.
(via propranolol )
anti-arrhythmia drug
A drug used for the treatment or prevention of cardiac arrhythmias. Anti-arrhythmia drugs may affect the polarisation-repolarisation phase of the action potential, its excitability or refractoriness, or impulse conduction or membrane responsiveness within cardiac fibres.
(via propranolol )
vasodilator agent
A drug used to cause dilation of the blood vessels.
(via propranolol )
View more via ChEBI Ontology
ChEBI Ontology
Outgoing (R)-(+)-propranolol (CHEBI:8736) is a propranolol (CHEBI:8499)
Incoming dexpropranolol hydrochloride (CHEBI:51161) has part (R)-(+)-propranolol (CHEBI:8736)
IUPAC Name
(2R)-3-(naphthalen-1-yloxy)-1-(propan-2-ylamino)propan-2-ol
INNs Sources
dexpropranolol ChEBI
dexpropranolol WHO MedNet
dexpropranololum WHO MedNet
Synonyms Sources
(+)-1-Isopropylamino-3-(1-naphthyloxy)-2-propanol ChemIDplus
(+)-Propranolol ChemIDplus
2R-Propranolol ChemIDplus
D-Propranolol ChemIDplus
Dexpropranolol KEGG COMPOUND
Dextropropranolol ChemIDplus
R (+)-Propanolol KEGG COMPOUND
R-(+)-Propranolol KEGG COMPOUND
Manual Xrefs Databases
C11193 KEGG COMPOUND
DB00571 DrugBank
LSM-5972 LINCS
View more database links
Registry Numbers Types Sources
4140099 Beilstein Registry Number Beilstein
5051-22-9 CAS Registry Number KEGG COMPOUND
5051-22-9 CAS Registry Number ChemIDplus
Last Modified
25 February 2016