CHEBI:28499 - kaempferol

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ChEBI Name kaempferol
ChEBI ID CHEBI:28499
Definition A tetrahydroxyflavone in which the four hydroxy groups are located at positions 3, 5, 7 and 4'. Acting as an antioxidant by reducing oxidative stress, it is currently under consideration as a possible cancer treatment.
Stars This entity has been manually annotated by the ChEBI Team.
Secondary ChEBI IDs CHEBI:43598, CHEBI:24944, CHEBI:6100
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Formula C15H10O6
Net Charge 0
Average Mass 286.23630
Monoisotopic Mass 286.04774
InChI InChI=1S/C15H10O6/c16-8-3-1-7(2-4-8)15-14(20)13(19)12-10(18)5-9(17)6-11(12)21-15/h1-6,16-18,20H
InChIKey IYRMWMYZSQPJKC-UHFFFAOYSA-N
SMILES Oc1ccc(cc1)-c1oc2cc(O)cc(O)c2c(=O)c1O
Metabolite of Species Details
Pittocaulon velatum (IPNI:238587-1) Found in stem (BTO:0001300). Methanol extract of dried and ground stems and roots See: PubMed
Pittocaulon velatum (IPNI:238587-1) Found in root (BTO:0001188). Methanol extract of dried and ground stems and roots See: PubMed
Ficus mucuso (NCBI:txid309328) Found in fruit (BTO:0000486). Methanolic extract of air-dried and powdered figs(fruits) See: PubMed
Homo sapiens (NCBI:txid9606) Found in urine (BTO:0001419). See: PubMed
Homo sapiens (NCBI:txid9606) Found in blood (UBERON:0000178). See: PubMed
Roles Classification
Biological Role(s): antibacterial agent
A substance (or active part thereof) that kills or slows the growth of bacteria.
human xenobiotic metabolite
Any human metabolite produced by metabolism of a xenobiotic compound in humans.
human urinary metabolite
Any metabolite (endogenous or exogenous) found in human urine samples.
human blood serum metabolite
Any metabolite (endogenous or exogenous) found in human blood serum samples.
plant metabolite
Any eukaryotic metabolite produced during a metabolic reaction in plants, the kingdom that include flowering plants, conifers and other gymnosperms.
Application(s): geroprotector
Any compound that supports healthy aging, slows the biological aging process, or extends lifespan.
View more via ChEBI Ontology
ChEBI Ontology
Outgoing kaempferol (CHEBI:28499) has role antibacterial agent (CHEBI:33282)
kaempferol (CHEBI:28499) has role geroprotector (CHEBI:176497)
kaempferol (CHEBI:28499) has role human blood serum metabolite (CHEBI:85234)
kaempferol (CHEBI:28499) has role human urinary metabolite (CHEBI:84087)
kaempferol (CHEBI:28499) has role human xenobiotic metabolite (CHEBI:76967)
kaempferol (CHEBI:28499) has role plant metabolite (CHEBI:76924)
kaempferol (CHEBI:28499) is a 7-hydroxyflavonol (CHEBI:52267)
kaempferol (CHEBI:28499) is a flavonols (CHEBI:28802)
kaempferol (CHEBI:28499) is a tetrahydroxyflavone (CHEBI:38684)
kaempferol (CHEBI:28499) is conjugate acid of kaempferol oxoanion (CHEBI:58573)
Incoming (+)-dihydrokaempferol (CHEBI:15401) has functional parent kaempferol (CHEBI:28499)
3,4'-dimethylkaempferol (CHEBI:146142) has functional parent kaempferol (CHEBI:28499)
4',5,7-trihydroxy-3-methoxyflavone-7-O-β-D-glucopyranoside (CHEBI:68351) has functional parent kaempferol (CHEBI:28499)
4',5,7-trihydroxy-3-methoxyflavone-7-O-rutinoside (CHEBI:68350) has functional parent kaempferol (CHEBI:28499)
563476_TEMP_6-hydroxykaempferol (CHEBI:563476) has functional parent kaempferol (CHEBI:28499)
6''-malonylastragalin (CHEBI:142248) has functional parent kaempferol (CHEBI:28499)
6''-O-acetylgenistin (CHEBI:142249) has functional parent kaempferol (CHEBI:28499)
6-hydroxykaempferol (CHEBI:28713) has functional parent kaempferol (CHEBI:28499)
7,4'-dimethylkaempferol (CHEBI:146145) has functional parent kaempferol (CHEBI:28499)
8-lavandulylkaempferol (CHEBI:66558) has functional parent kaempferol (CHEBI:28499)
afzelin (CHEBI:80790) has functional parent kaempferol (CHEBI:28499)
cudranian 1 (CHEBI:65687) has functional parent kaempferol (CHEBI:28499)
herbacetin (CHEBI:27673) has functional parent kaempferol (CHEBI:28499)
hermannioside B (CHEBI:69378) has functional parent kaempferol (CHEBI:28499)
kaempferide (CHEBI:6099) has functional parent kaempferol (CHEBI:28499)
kaempferol 3,7-di-O-α-L-rhamnoside (CHEBI:68883) has functional parent kaempferol (CHEBI:28499)
kaempferol 3-O-α-L-arabinopyranosyl-7-O-α-L-rhamnopyranoside (CHEBI:68878) has functional parent kaempferol (CHEBI:28499)
kaempferol 3-O-β-D-allopyranoside (CHEBI:75796) has functional parent kaempferol (CHEBI:28499)
kaempferol 3-O-β-D-apiofuranosyl-7-O-α-L-rhamnopyranoside (CHEBI:68884) has functional parent kaempferol (CHEBI:28499)
kaempferol 3-O-β-D-galactopyranosyl-7-O-α-L-rhamnopyranoside (CHEBI:68881) has functional parent kaempferol (CHEBI:28499)
kaempferol 3-O-β-D-galactoside (CHEBI:31742) has functional parent kaempferol (CHEBI:28499)
kaempferol 3-O-β-D-glucosylgalactoside (CHEBI:80528) has functional parent kaempferol (CHEBI:28499)
kaempferol 3-O-β-D-xyloside (CHEBI:76294) has functional parent kaempferol (CHEBI:28499)
kaempferol 3-O-(5-O-acetyl-α-D-apiofuranosyl)-7-O-α-L-rhamnopyranoside (CHEBI:68877) has functional parent kaempferol (CHEBI:28499)
kaempferol 3-O-[α-L-rhamnopyranosyl(1→2)-β-D-galactopyranosyl]-7-O-α-L-rhamnopyranoside (CHEBI:68880) has functional parent kaempferol (CHEBI:28499)
kaempferol 3-O-[6-(4-coumaroyl)-β-D-glucosyl-(1→2)-β-D-glucosyl-(1→2)-β-D-glucoside] (CHEBI:31741) has functional parent kaempferol (CHEBI:28499)
kaempferol 3-O-gentiobioside-7-O-rhamnoside (CHEBI:133218) has functional parent kaempferol (CHEBI:28499)
kaempferol 7-O-β-D-galactopyranoside (CHEBI:75794) has functional parent kaempferol (CHEBI:28499)
kaempferol O-glucoside (CHEBI:64634) has functional parent kaempferol (CHEBI:28499)
kaempferol O-glucuronide (CHEBI:75720) has functional parent kaempferol (CHEBI:28499)
multiflorin B (CHEBI:81208) has functional parent kaempferol (CHEBI:28499)
rhamnocitrin (CHEBI:80897) has functional parent kaempferol (CHEBI:28499)
robinin (CHEBI:8878) has functional parent kaempferol (CHEBI:28499)
sexangularetin (CHEBI:9131) has functional parent kaempferol (CHEBI:28499)
tribuloside (CHEBI:80944) has functional parent kaempferol (CHEBI:28499)
kaempferol oxoanion (CHEBI:58573) is conjugate base of kaempferol (CHEBI:28499)
IUPAC Name
3,5,7-trihydroxy-2-(4-hydroxyphenyl)-4H-chromen-4-one
Synonyms Sources
3,4',5,7-Tetrahydroxyflavone KEGG COMPOUND
4H-1-Benzopyran-4-one, 3,5,7-trihydroxy-2-(4-hydroxyphenyl)-5,7,4'-Trihydroxyflavonol KEGG COMPOUND
5,7,4'-trihydroxyflavonol ChemIDplus
C.I. 75640 KEGG COMPOUND
campherol ChemIDplus
Indigo yellow KEGG COMPOUND
Kaempferol KEGG COMPOUND
Kaempherol KEGG COMPOUND
Kämpferol ChEBI
Kampherol HMDB
Kempferol KEGG COMPOUND
Nimbecetin KEGG COMPOUND
Pelargidenolon KEGG COMPOUND
Populnetin KEGG COMPOUND
Rhamnolutein KEGG COMPOUND
Rhamnolutin KEGG COMPOUND
Robigenin KEGG COMPOUND
Swartziol KEGG COMPOUND
Trifolitin KEGG COMPOUND
Manual Xrefs Databases
C00004565 KNApSAcK
C05903 KEGG COMPOUND
CPD1F-90 MetaCyc
DB01852 DrugBank
HMDB0005801 HMDB
kaempferol Wikipedia
KMP PDBeChem
LMPK12110003 LIPID MAPS
LSM-5304 LINCS
View more database links
Registry Numbers Types Sources
304401 Reaxys Registry Number Reaxys
520-18-3 CAS Registry Number KEGG COMPOUND
520-18-3 CAS Registry Number ChemIDplus
Citations Waiting for Citations Types Sources
12592675 PubMed citation Europe PMC
15234754 PubMed citation Europe PMC
17426744 PubMed citation Europe PMC
17551714 PubMed citation Europe PMC
28166217 PubMed citation Europe PMC
Last Modified
26 October 2021