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InChI=1S/CH4O/c1-2/h2H,1H3
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> Main
CHEBI:37945 - dibekacin
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ChEBI Ontology
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ChEBI Name
dibekacin
ChEBI ID
CHEBI:37945
Definition
A kanamycin that is kanamycin B lacking the 3- and 4-hydroxy groups on the 2,6-diaminosugar ring.
Stars
This entity has been manually annotated by the ChEBI Team.
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Formula
C18H37N5O8
Net Charge
0
Average Mass
451.51528
Monoisotopic Mass
451.26421
InChI
InChI=1S/C18H37N5O8/c19-
4-
6-
1-
2-
7(20)
17(28-
6)
30-
15-
8(21)
3-
9(22)
16(14(15)
27)
31-
18-
13(26)
11(23)
12(25)
10(5-
24)
29-
18/h6-
18,24-
27H,1-
5,19-
23H2/t6-
,7+,8-
,9+,10+,11-
,12+,13+,14-
,15+,16-
,17+,18+/m0/s1
InChIKey
JJCQSGDBDPYCEO-XVZSLQNASA-N
SMILES
NC[C@@H]
1CC[C@@H]
(N)
[C@H]
(O1)
O[C@@H]
1[C@@H]
(N)
C[C@@H]
(N)
[C@H]
(O[C@H]
2O[C@H]
(CO)
[C@@H]
(O)
[C@H]
(N)
[C@H]
2O)
[C@H]
1O
Roles Classification
Biological Role
(s):
protein synthesis inhibitor
A compound, usually an anti-bacterial agent or a toxin, which inhibits the synthesis of a protein.
antibacterial agent
A substance (or active part thereof) that kills or slows the growth of bacteria.
antimicrobial agent
A substance that kills or slows the growth of microorganisms, including bacteria, viruses, fungi and protozoans.
(via
carbohydrate-containing antibiotic
)
View more via ChEBI Ontology
ChEBI Ontology
Outgoing
dibekacin (
CHEBI:37945
)
has functional parent
kanamycin B (
CHEBI:28098
)
dibekacin (
CHEBI:37945
)
has role
antibacterial agent (
CHEBI:33282
)
dibekacin (
CHEBI:37945
)
has role
protein synthesis inhibitor (
CHEBI:48001
)
dibekacin (
CHEBI:37945
)
is a
kanamycins (
CHEBI:24951
)
Incoming
dibekacin sulfate (
CHEBI:31475
)
has functional parent
dibekacin (
CHEBI:37945
)
IUPAC Name
(1
R
,2
S
,3
S
,4
R
,6
S
)-
4,6-
diamino-
3-
(3-
amino-
3-
deoxy-
α-
D
-
glucopyranosyloxy)-
2-
hydroxycyclohexyl 2,6-
diamino-
2,3,4,6-
tetradeoxy-
α-
D
-
erythro
-
hexopyranoside
INN
Source
dibekacin
KEGG DRUG
Synonyms
Sources
3',4'-Dideoxykanamycin B
ChemIDplus
DKM
KEGG DRUG
O-
3-
Amino-
3-
deoxy-
alpha-
D-
glucopyranosyl-
(1-
4)-
O-
(2,6-
diamino-
2,3,4,6-
tetradeoxy-
alpha-
D-
erythro-
hexopyranosyl-
(1-
6))-
2-
deoxy-
L-
streptamine
ChemIDplus
Panamicin
ChemIDplus
Manual Xrefs
Databases
855
DrugCentral
CN101278900
Patent
CN101575354
Patent
D07811
KEGG DRUG
View more database links
Registry Numbers
Types
Sources
1441606
Reaxys Registry Number
Reaxys
34493-98-6
CAS Registry Number
ChemIDplus
Citations
Types
Sources
20922036
PubMed citation
Europe PMC
20936279
PubMed citation
Europe PMC
Last Modified
22 February 2017