A 4-{2-[4-(3,10-dibromo-8-chloro-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl)piperidin-1-yl]-2-oxoethyl}piperidine-1-carboxamide that has R configuration. It is used as oral farnesyltransferase inhibitor.
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This entity has been manually annotated by the ChEBI Team.
An EC 2.5.1.* (non-methyl-alkyl or aryl transferase) inhibitor that interferes with the action of protein farnesyltransferase (EC 2.5.1.58), one of the three enzymes in the prenyltransferase group.
lonafarnib
(CHEBI:47097)
has role
antineoplastic agent
(CHEBI:35610)
lonafarnib
(CHEBI:47097)
has role
EC 2.5.1.58 (protein farnesyltransferase) inhibitor
(CHEBI:64133)
lonafarnib
(CHEBI:47097)
is a
4-{2-[4-(3,10-dibromo-8-chloro-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl)piperidin-1-yl]-2-oxoethyl}piperidine-1-carboxamide
(CHEBI:90678)