CHEBI:7622 - norathyriol

Main ChEBI Ontology Automatic Xrefs Reactions Pathways Models
ChEBI Name norathyriol
ChEBI ID CHEBI:7622
Definition A member of the class of xanthones that is 9H-xanthen-9-one substituted by hydroxy groups at positions 1, 3, 6 and 7. Isolated from Garcinia mangostana and Maclura pomifera, it exhibits inhibitory activity against protein kinase C.
Stars This entity has been manually annotated by the ChEBI Team.
Secondary ChEBI IDs CHEBI:66635
Supplier Information
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Formula C13H8O6
Net Charge 0
Average Mass 260.19900
Monoisotopic Mass 260.03209
InChI InChI=1S/C13H8O6/c14-5-1-9(17)12-11(2-5)19-10-4-8(16)7(15)3-6(10)13(12)18/h1-4,14-17H
InChIKey ZHTQCPCDXKMMLU-UHFFFAOYSA-N
SMILES Oc1cc(O)c2c(c1)oc1cc(O)c(O)cc1c2=O
Metabolite of Species Details
Chlorophora tinctoria (IPNI:1131012-2) See: DOI
Morus tinctoria (IPNI:164496-2) See: DOI
Athyrium mesosorum (IPNI:17055670-1) See: PubMed
Canscora decussata (IPNI:366549-1) See: DOI
Garcinia echinocarpa (IPNI:427934-1) See: DOI
Garcinia pedunculata (IPNI:428166-1) See: DOI
Garcinia terpnophylla (IPNI:428266-1) See: DOI
Cratoxylum pruniflorum (IPNI:433071-1) See: PHARMAZIE,1988,43,879
Hypericum aucheri (IPNI:433222-1) See: KHIMIYA PRIRODNYKH SOEDINENII,1980,2,256
Garcinia multiflora (NCBI:txid1009474) See: DOI
Hypericum androsaemum (NCBI:txid140968) See: DOI
Symphonia globulifera (NCBI:txid156483) See: DOI
Anaxagorea luzonensis (NCBI:txid235716) See: NATURAL MEDICINES,2001,55,316
Hypericum japonicum (NCBI:txid282542) See: NAT PROD RES DEV,2004,16,511
Hypericum sampsonii (NCBI:txid282553) See: PubMed
Maclura pomifera (NCBI:txid3496) See: DOI
Allanblackia floribunda (NCBI:txid469914) See: DOI
Ochrocarpos (NCBI:txid469946) See: DOI
Pentaphalangium (NCBI:txid58227) See: DOI
Garcinia mangostana (NCBI:txid58228) See: DOI
Tripterospermum lanceolatum (NCBI:txid933376) See: PubMed
Gymnocarpium robertianum (NCBI:txid983334) See: YAKUGAKU ZASSHI,1986,106,378
Iris nigricans (NCBI:txid995810) See: DOI
Mammea africana (NCBI:txid999584) See: DOI
Roles Classification
Biological Role(s): EC 2.7.11.13 (protein kinase C) inhibitor
An EC 2.7.11.* (protein-serine/threonine kinase) inhibitor that interferes with the action of protein kinase C (EC 2.7.11.13).
plant metabolite
Any eukaryotic metabolite produced during a metabolic reaction in plants, the kingdom that include flowering plants, conifers and other gymnosperms.
Application(s): antineoplastic agent
A substance that inhibits or prevents the proliferation of neoplasms.
View more via ChEBI Ontology
ChEBI Ontology
Outgoing norathyriol (CHEBI:7622) has role antineoplastic agent (CHEBI:35610)
norathyriol (CHEBI:7622) has role EC 2.7.11.13 (protein kinase C) inhibitor (CHEBI:37700)
norathyriol (CHEBI:7622) has role plant metabolite (CHEBI:76924)
norathyriol (CHEBI:7622) is a polyphenol (CHEBI:26195)
norathyriol (CHEBI:7622) is a xanthones (CHEBI:51149)
Incoming tripteroside (CHEBI:9746) has functional parent norathyriol (CHEBI:7622)
IUPAC Name
1,3,6,7-tetrahydroxy-9H-xanthen-9-one
Synonyms Sources
1,3,6,7-tetrahydroxyxanthone ChEBI
1,3,6,7-Tetrahydroxyxanthone KEGG COMPOUND
Norathyriol KEGG COMPOUND
Manual Xrefs Databases
C00002968 KNApSAcK
C10086 KEGG COMPOUND
CN102657640 Patent
View more database links
Registry Numbers Types Sources
270886 Reaxys Registry Number Reaxys
3542-72-1 CAS Registry Number ChemIDplus
Citations Waiting for Citations Types Sources
13995190 PubMed citation Europe PMC
15256712 PubMed citation Europe PMC
20513373 PubMed citation Europe PMC
22084399 PubMed citation Europe PMC
23361275 PubMed citation Europe PMC
7511107 PubMed citation Europe PMC
9384257 PubMed citation Europe PMC
Last Modified
03 October 2014
General Comments
2012-07-27 YAKUGAKU ZASSHI,1986,106,378
2012-07-27 NAT PROD RES DEV,2004,16,511
2012-07-27 KHIMIYA PRIRODNYKH SOEDINENII,1980,2,256
2012-07-27 PHARMAZIE,1988,43,879
2012-07-27 NATURAL MEDICINES,2001,55,316