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paromomycin |
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CHEBI:7934 |
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An amino cyclitol glycoside that is the 1-O-(2-amino-2-deoxy-α-D-glucopyranoside) and the 3-O-(2,6-diamino-2,6-dideoxy-β-L-idopyranosyl)-β-D-ribofuranoside of 4,6-diamino-2,3-dihydroxycyclohexane (the 1R,2R,3S,4R,6S diastereoisomer). It is obtained from various Streptomyces species. A broad-spectrum antibiotic, it is used (generally as the sulfate salt) for the treatment of acute and chronic intestinal protozoal infections, but is not effective for extraintestinal protozoal infections. It is also used as a therapeutic against visceral leishmaniasis. |
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This entity has been manually annotated by the ChEBI Team.
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CHEBI:44703
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Molfile
XML
SDF
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more structures >>
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InChI=1S/C23H45N5O14/c24- 2- 7- 13(32) 15(34) 10(27) 21(37- 7) 41- 19- 9(4- 30) 39- 23(17(19) 36) 42- 20- 12(31) 5(25) 1- 6(26) 18(20) 40- 22- 11(28) 16(35) 14(33) 8(3- 29) 38- 22/h5- 23,29- 36H,1- 4,24- 28H2/t5- ,6+,7+,8- ,9- ,10- ,11- ,12+,13- ,14- ,15- ,16- ,17- ,18- ,19- ,20- ,21- ,22- ,23+/m1/s1 |
UOZODPSAJZTQNH-LSWIJEOBSA-N |
NC[C@@H] 1O[C@H] (O[C@@H] 2[C@@H] (CO) O[C@@H] (O[C@@H] 3[C@@H] (O) [C@H] (N) C[C@H] (N) [C@H] 3O[C@H] 3O[C@H] (CO) [C@@H] (O) [C@H] (O) [C@H] 3N) [C@@H] 2O) [C@H] (N) [C@@H] (O) [C@@H] 1O |
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antibacterial drug
A drug used to treat or prevent bacterial infections.
antiprotozoal drug
Any antimicrobial drug which is used to treat or prevent protozoal infections.
antimicrobial agent
A substance that kills or slows the growth of microorganisms, including bacteria, viruses, fungi and protozoans.
(via carbohydrate-containing antibiotic )
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antibacterial drug
A drug used to treat or prevent bacterial infections.
antiprotozoal drug
Any antimicrobial drug which is used to treat or prevent protozoal infections.
anthelminthic drug
Substance intended to kill parasitic worms (helminths).
antiparasitic agent
A substance used to treat or prevent parasitic infections.
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View more via ChEBI Ontology
(1R,2R,3S,4R,6S)- 4,6- diamino- 2- {[3- O- (2,6- diamino- 2,6- dideoxy- β- L- idopyranosyl)- β- D- ribofuranosyl]oxy}- 3- hydroxycyclohexyl 2- amino- 2- deoxy- α- D- glucopyranoside
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paromomicina
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ChemIDplus
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paromomycin
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WHO MedNet
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paromomycine
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ChemIDplus
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paromomycinum
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ChemIDplus
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(1R,2R,3S,4R,6S)- 4,6- diamino- 2- {[3- O- (2,6- diamino- 2,6- dideoxy- beta- L- idopyranosyl)- beta- D- ribofuranosyl]oxy}- 3- hydroxycyclohexyl 2- amino- 2- deoxy- alpha- D- glucopyranoside
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PDBeChem
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Aminosidin
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KEGG COMPOUND
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aminosidine
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ChemIDplus
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Catenulin
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KEGG COMPOUND
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crestomycin
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ChemIDplus
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estomycin
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ChemIDplus
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hydroxymycin
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ChemIDplus
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Hydroxymycin
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KEGG COMPOUND
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Monomycin A
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KEGG COMPOUND
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neomycin E
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ChemIDplus
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Neomycin E
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KEGG COMPOUND
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PAROMOMYCIN
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PDBeChem
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Paromomycin
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KEGG COMPOUND
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Paromomycin I
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KEGG COMPOUND
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paucimycin
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ChemIDplus
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paucimycinum
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ChemIDplus
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R 400
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ChemIDplus
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R-400
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ChEBI
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Zygomycin A1
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KEGG COMPOUND
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2067
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DrugCentral
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C00832
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KEGG COMPOUND
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D07467
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KEGG DRUG
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DB01421
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DrugBank
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PAR
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PDBeChem
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US2895876
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Patent
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US2916485
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Patent
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View more database links |
72285
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Reaxys Registry Number
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Reaxys
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7542-37-2
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CAS Registry Number
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ChemIDplus
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18447603
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PubMed citation
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Europe PMC
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18947845
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PubMed citation
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Europe PMC
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8036682
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PubMed citation
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Europe PMC
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