Activities

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45
Inhibition
12
Activity
57
ORGANISM
57
Eukaryotes
57
Mammalia
57
Rodentia
45
Rattus norvegicus
12
Mus musculus
57
organism-based format
57
N/A
5
Approved
52
Preclinical
0
N/A
57
0
0
N/A
5
[2,3)
34
[3,4)
18
[4,4.7]
0
N/A
5
[208,240)
5
[240,256)
5
[256,288)
10
[288,304)
10
[304,320)
4
[320,336)
14
[336,368)
4
[368,381.07]
57
Scientific Literature
Showing 1-20 out of 57 records
#Molecule ChEMBL IDCompound KeyStandard TypeStandard RelationStandard ValueStandard Text ValueStandard UnitspChEMBL ValueCommentAssay ChEMBL IDAssay DescriptionBAO LabelAssay OrganismTarget ChEMBL IDTarget NameTarget OrganismTarget TypeDocument ChEMBL IDSource DescriptionCell ChEMBL ID
1.
1
Inhibition
=
38.8
---
%
---
---
Antiinflammatory activity in albino rat assessed as inhibition of carrageenan-induced paw oedema at 100 mg/kg, po measured after 180 mins of carrageenan challenge relative to control
organism-based format
Rattus norvegicus
Rattus norvegicus
Rattus norvegicus
ORGANISM
Scientific Literature
2.
7
Inhibition
=
17.6
---
%
---
---
Antiinflammatory activity in albino rat assessed as inhibition of carrageenan-induced paw oedema at 100 mg/kg, po measured after 120 mins of carrageenan challenge relative to control
organism-based format
Rattus norvegicus
Rattus norvegicus
Rattus norvegicus
ORGANISM
Scientific Literature
3.
8
Inhibition
=
20.0
---
%
---
---
Antiinflammatory activity in albino rat assessed as inhibition of carrageenan-induced paw oedema at 100 mg/kg, po measured after 60 mins of carrageenan challenge relative to control
organism-based format
Rattus norvegicus
Rattus norvegicus
Rattus norvegicus
ORGANISM
Scientific Literature
4.
8
Inhibition
=
23.5
---
%
---
---
Antiinflammatory activity in albino rat assessed as inhibition of carrageenan-induced paw oedema at 100 mg/kg, po measured after 120 mins of carrageenan challenge relative to control
organism-based format
Rattus norvegicus
Rattus norvegicus
Rattus norvegicus
ORGANISM
Scientific Literature
5.
8
Activity
=
85.66
---
%
---
---
Analgesic activity in Swiss albino mouse assessed as protection against acetic acid-induced writhing at 100 mg/kg, po administered 1 hr prior to acetic acid challenge relative to control measured after 3 hrs
organism-based format
Mus musculus
Mus musculus
Mus musculus
ORGANISM
Scientific Literature
6.
1
Inhibition
=
41.1
---
%
---
---
Antiinflammatory activity in albino rat assessed as inhibition of carrageenan-induced paw oedema at 100 mg/kg, po measured after 120 mins of carrageenan challenge relative to control
organism-based format
Rattus norvegicus
Rattus norvegicus
Rattus norvegicus
ORGANISM
Scientific Literature
7.
2
Inhibition
=
41.1
---
%
---
---
Antiinflammatory activity in albino rat assessed as inhibition of carrageenan-induced paw oedema at 100 mg/kg, po measured after 120 mins of carrageenan challenge relative to control
organism-based format
Rattus norvegicus
Rattus norvegicus
Rattus norvegicus
ORGANISM
Scientific Literature
8.
9
Inhibition
=
13.3
---
%
---
---
Antiinflammatory activity in albino rat assessed as inhibition of carrageenan-induced paw oedema at 100 mg/kg, po measured after 60 mins of carrageenan challenge relative to control
organism-based format
Rattus norvegicus
Rattus norvegicus
Rattus norvegicus
ORGANISM
Scientific Literature
9.
11
Inhibition
=
22.2
---
%
---
---
Antiinflammatory activity in albino rat assessed as inhibition of carrageenan-induced paw oedema at 100 mg/kg, po measured after 180 mins of carrageenan challenge relative to control
organism-based format
Rattus norvegicus
Rattus norvegicus
Rattus norvegicus
ORGANISM
Scientific Literature
10.
4
Inhibition
=
29.4
---
%
---
---
Antiinflammatory activity in albino rat assessed as inhibition of carrageenan-induced paw oedema at 100 mg/kg, po measured after 120 mins of carrageenan challenge relative to control
organism-based format
Rattus norvegicus
Rattus norvegicus
Rattus norvegicus
ORGANISM
Scientific Literature
11.
6
Inhibition
=
20.0
---
%
---
---
Antiinflammatory activity in albino rat assessed as inhibition of carrageenan-induced paw oedema at 100 mg/kg, po measured after 60 mins of carrageenan challenge relative to control
organism-based format
Rattus norvegicus
Rattus norvegicus
Rattus norvegicus
ORGANISM
Scientific Literature
12.
6
Inhibition
=
22.2
---
%
---
---
Antiinflammatory activity in albino rat assessed as inhibition of carrageenan-induced paw oedema at 100 mg/kg, po measured after 180 mins of carrageenan challenge relative to control
organism-based format
Rattus norvegicus
Rattus norvegicus
Rattus norvegicus
ORGANISM
Scientific Literature
13.
8
Inhibition
=
16.6
---
%
---
---
Antiinflammatory activity in albino rat assessed as inhibition of carrageenan-induced paw oedema at 100 mg/kg, po measured after 180 mins of carrageenan challenge relative to control
organism-based format
Rattus norvegicus
Rattus norvegicus
Rattus norvegicus
ORGANISM
Scientific Literature
14.
10
Inhibition
=
23.5
---
%
---
---
Antiinflammatory activity in albino rat assessed as inhibition of carrageenan-induced paw oedema at 100 mg/kg, po measured after 120 mins of carrageenan challenge relative to control
organism-based format
Rattus norvegicus
Rattus norvegicus
Rattus norvegicus
ORGANISM
Scientific Literature
15.
1
Activity
=
72.33
---
%
---
---
Analgesic activity in Swiss albino mouse assessed as protection against acetic acid-induced writhing at 100 mg/kg, po administered 1 hr prior to acetic acid challenge relative to control measured after 3 hrs
organism-based format
Mus musculus
Mus musculus
Mus musculus
ORGANISM
Scientific Literature
16.
10
Inhibition
=
7.6
---
%
---
---
Antiinflammatory activity in albino rat assessed as inhibition of carrageenan-induced paw oedema at 100 mg/kg, po measured after 30 mins of carrageenan challenge relative to control
organism-based format
Rattus norvegicus
Rattus norvegicus
Rattus norvegicus
ORGANISM
Scientific Literature
17.
10
Inhibition
=
20.0
---
%
---
---
Antiinflammatory activity in albino rat assessed as inhibition of carrageenan-induced paw oedema at 100 mg/kg, po measured after 60 mins of carrageenan challenge relative to control
organism-based format
Rattus norvegicus
Rattus norvegicus
Rattus norvegicus
ORGANISM
Scientific Literature
18.
3
Inhibition
=
7.6
---
%
---
---
Antiinflammatory activity in albino rat assessed as inhibition of carrageenan-induced paw oedema at 100 mg/kg, po measured after 30 mins of carrageenan challenge relative to control
organism-based format
Rattus norvegicus
Rattus norvegicus
Rattus norvegicus
ORGANISM
Scientific Literature
19.
4
Inhibition
=
26.6
---
%
---
---
Antiinflammatory activity in albino rat assessed as inhibition of carrageenan-induced paw oedema at 100 mg/kg, po measured after 60 mins of carrageenan challenge relative to control
organism-based format
Rattus norvegicus
Rattus norvegicus
Rattus norvegicus
ORGANISM
Scientific Literature
20.
10
Activity
=
88.0
---
%
---
---
Analgesic activity in Swiss albino mouse assessed as protection against acetic acid-induced writhing at 100 mg/kg, po administered 1 hr prior to acetic acid challenge relative to control measured after 3 hrs
organism-based format
Mus musculus
Mus musculus
Mus musculus
ORGANISM
Scientific Literature
Showing 1-20 out of 57 records
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