Activities
58 items
You are exploring a subset of activities:
Activities related to compound CHEMBL347862 (CARBOXYMETHOXYLAMINE) and its 2 alternative forms.
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Showing 1-20
out of 58 records
| # | Molecule ChEMBL ID | Compound Key | Standard Type | Standard Relation | Standard Value | Standard Text Value | Standard Units | pChEMBL Value | Comment | Assay ChEMBL ID | Assay Description | BAO Label | Assay Organism | Target ChEMBL ID | Target Name | Target Organism | Target Type | Document ChEMBL ID | Source Description | Cell ChEMBL ID | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |
SID50105722
|
Potency
|
=
|
707945.8
|
---
|
nM
|
3.15
|
Inconclusive
|
PUBCHEM_BIOASSAY: Total Fluorescence Counterscreen for Inhibitors of the Interaction of Thyroid Hormone Receptor and Steroid Receptor Coregulator 2. (Class of assay: confirmatory)
|
assay format
|
Homo sapiens
|
Thyroid hormone receptor beta-1
|
Homo sapiens
|
SINGLE PROTEIN
|
PubChem BioAssays
| ||||||
| 2. |
O-(Carboxymethyl)hydroxylamine hemihydrochloride
|
Inhibition
|
---
|
---
|
---
|
%
|
---
|
Not Active
|
Inhibition of neurosphere proliferation of mouse neural precursor cells by MTT assay
|
assay format
|
Mus musculus
|
Unchecked
|
---
|
UNCHECKED
|
Scientific Literature
| ||||||
| 3. |
SID50105722
|
Potency
|
=
|
11220.2
|
---
|
nM
|
4.95
|
Inconclusive
|
PUBCHEM_BIOASSAY: qHTS for differential inhibitors of proliferation of Plasmodium falciparum line D10. (Class of assay: confirmatory) [Related PubChem assays: 1815 (Assay for Plasmodium falciparum line 7G8), 1816 (Assay for Plasmodium falciparum line GB4), 1828 (Summary assay)]
|
assay format
|
---
|
NON-PROTEIN TARGET
|
---
|
NON-MOLECULAR
|
PubChem BioAssays
| ||||||
| 4. |
SID57265700
|
Potency
|
---
|
37685.8
|
---
|
nM
|
---
|
inactive
|
PubChem BioAssay. qHTS Assay for Inhibitors of the Human Apurinic/apyrimidinic Endonuclease 1 (APE1). (Class of assay: confirmatory)
|
assay format
|
---
|
DNA-(apurinic or apyrimidinic site) lyase
|
Homo sapiens
|
SINGLE PROTEIN
|
PubChem BioAssays
| ||||||
| 5. |
SID57265700
|
Potency
|
---
|
22387.2
|
---
|
nM
|
---
|
Active
|
PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of JMJD2A-Tudor Domain. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504402]
|
assay format
|
Homo sapiens
|
Lysine-specific demethylase 4A
|
Homo sapiens
|
SINGLE PROTEIN
|
PubChem BioAssays
| ||||||
| 6. |
SID50105722
|
Potency
|
---
|
3162.3
|
---
|
nM
|
---
|
Active
|
PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Histone Lysine Methyltransferase G9a. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504404]
|
assay format
|
Homo sapiens
|
Histone-lysine N-methyltransferase, H3 lysine-9 specific 3
|
Homo sapiens
|
SINGLE PROTEIN
|
PubChem BioAssays
| ||||||
| 7. |
NCGC00093533-01
|
IC50
|
=
|
10000.0
|
---
|
nM
|
5.00
|
---
|
Antiplasmodial activity against Plasmodium falciparum D10 after 72 hrs by SYBR green assay
|
organism-based format
|
Plasmodium falciparum
|
Plasmodium falciparum
|
Plasmodium falciparum
|
ORGANISM
|
Scientific Literature
| ||||||
| 8. |
NCGC00093533-01
|
IC50
|
=
|
12589.25
|
---
|
nM
|
4.90
|
---
|
Antiplasmodial activity against Plasmodium falciparum W2 after 72 hrs by SYBR green assay
|
organism-based format
|
Plasmodium falciparum
|
Plasmodium falciparum
|
Plasmodium falciparum
|
ORGANISM
|
Scientific Literature
| ||||||
| 9. |
NCGC00093533-01
|
IC50
|
=
|
10000.0
|
---
|
nM
|
5.00
|
---
|
Antiplasmodial activity against Plasmodium falciparum 3D7 after 72 hrs by SYBR green assay
|
organism-based format
|
Plasmodium falciparum
|
Plasmodium falciparum
|
Plasmodium falciparum
|
ORGANISM
|
Scientific Literature
| ||||||
| 10. |
SID50105722
|
Potency
|
---
|
18526.0
|
---
|
nM
|
---
|
inconclusive
|
PUBCHEM_BIOASSAY: Quantitative high throughput screen for delayed death inhibitors of the malarial parasite plastid, 48 hour incubation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488745, AID488774]
|
organism-based format
|
Plasmodium falciparum
|
Plasmodium falciparum
|
Plasmodium falciparum
|
ORGANISM
|
PubChem BioAssays
| ||||||
| 11. |
SID57265700
|
Potency
|
---
|
316.2
|
---
|
nM
|
---
|
inconclusive
|
PubChem BioAssay. qHTS of TDP-43 Inhibitors. (Class of assay: confirmatory)
|
assay format
|
---
|
TAR DNA-binding protein 43
|
Homo sapiens
|
SINGLE PROTEIN
|
PubChem BioAssays
| ||||||
| 12. |
SID50105722
|
Potency
|
---
|
3981.1
|
---
|
nM
|
---
|
inconclusive
|
PUBCHEM_BIOASSAY: qHTS for inhibitors of binding or entry into cells for Marburg Virus. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID463114, AID540249, AID540278]
|
assay format
|
---
|
Unchecked
|
---
|
UNCHECKED
|
PubChem BioAssays
| ||||||
| 13. |
SID57265700
|
Potency
|
---
|
50118.7
|
---
|
nM
|
---
|
inconclusive
|
PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of BAZ2B. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504391]
|
assay format
|
Homo sapiens
|
Bromodomain adjacent to zinc finger domain protein 2B
|
Homo sapiens
|
SINGLE PROTEIN
|
PubChem BioAssays
| ||||||
| 14. |
SID90340597
|
Potency
|
---
|
751.2
|
---
|
nM
|
---
|
inconclusive
|
PUBCHEM_BIOASSAY: Inhibitors of Regulator of G Protein Signaling (RGS) 4: qHTS. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504856]
|
assay format
|
---
|
Regulator of G-protein signaling 4
|
Homo sapiens
|
SINGLE PROTEIN
|
PubChem BioAssays
| ||||||
| 15. |
SID11110738
|
Potency
|
=
|
31622.8
|
---
|
nM
|
4.50
|
Inconclusive
|
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Thyroid Stimulating Hormone Receptor. (Class of assay: confirmatory)
|
assay format
|
Homo sapiens
|
Thyroid stimulating hormone receptor
|
Homo sapiens
|
SINGLE PROTEIN
|
PubChem BioAssays
| ||||||
| 16. |
AOAA
|
TGI
|
---
|
---
|
---
|
---
|
---
|
Active
|
Antitumor activity against human HT-29 cells xenografted in BALB/c nude mouse assessed as tumor growth inhibition at 10 mg/kg, sc administered once daily for 6 days followed by 1 day interval and subsequent dosing for 6 days
|
organism-based format
|
Homo sapiens
|
HT-29
|
Homo sapiens
|
CELL-LINE
|
Scientific Literature
| ||||||
| 17. |
SID50105722
|
Potency
|
=
|
12589.3
|
---
|
nM
|
4.90
|
Inconclusive
|
PUBCHEM_BIOASSAY: qHTS for differential inhibitors of proliferation of Plasmodium falciparum line HB3. (Class of assay: confirmatory) [Related PubChem assays: 1815 (Assay for Plasmodium falciparum line 7G8), 1877 (Assay for Plasmodium falciparum line D10), 1816 (Assay for Plasmodium falciparum line GB4), 1876 (Assay for Plasmodium falciparum line 3D7), 1828 (Summary assay)]
|
assay format
|
---
|
NON-PROTEIN TARGET
|
---
|
NON-MOLECULAR
|
PubChem BioAssays
| ||||||
| 18. |
SID50105722
|
Potency
|
=
|
8912.5
|
---
|
nM
|
5.05
|
Inconclusive
|
PUBCHEM_BIOASSAY: qHTS for differential inhibitors of proliferation of Plasmodium falciparum line 3D7. (Class of assay: confirmatory) [Related PubChem assays: 1815 (Assay for Plasmodium falciparum line 7G8), 1816 (Assay for Plasmodium falciparum line GB4), 1828 (Summary assay)]
|
assay format
|
---
|
NON-PROTEIN TARGET
|
---
|
NON-MOLECULAR
|
PubChem BioAssays
| ||||||
| 19. |
SID11110738
|
Potency
|
=
|
31622.8
|
---
|
nM
|
4.50
|
Inconclusive
|
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Thyroid Stimulating Hormone Receptor: Activators of Intracellular cAMP Concentrations in Parental HEK 293. (Class of assay: confirmatory)
|
assay format
|
Homo sapiens
|
Thyroid stimulating hormone receptor
|
Homo sapiens
|
SINGLE PROTEIN
|
PubChem BioAssays
| ||||||
| 20. |
SID50105722
|
Potency
|
=
|
14125.4
|
---
|
nM
|
4.85
|
Inconclusive
|
PUBCHEM_BIOASSAY: qHTS for differential inhibitors of proliferation of Plasmodium falciparum line W2. (Class of assay: confirmatory) [Related PubChem assays: 1815 (Assay for Plasmodium falciparum line 7G8), 1877 (Assay for Plasmodium falciparum line D10), 1816 (Assay for Plasmodium falciparum line GB4), 1876 (Assay for Plasmodium falciparum line 7D3), 1828 (Summary assay)]
|
assay format
|
---
|
NON-PROTEIN TARGET
|
---
|
NON-MOLECULAR
|
PubChem BioAssays
|
Showing 1-20
out of 58 records
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