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Activities related to compound CHEMBL451226 and its 1 alternative forms.

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Showing 1-20 out of 95 records

#	Molecule ChEMBL ID	Compound Key	Standard Type	Standard Relation	Standard Value	Standard Text Value	Standard Units	pChEMBL Value	Comment	Assay ChEMBL ID	Assay Description	BAO Label	Assay Organism	Target ChEMBL ID	Target Name	Target Organism	Target Type	Document ChEMBL ID	Source Description	Cell ChEMBL ID
1.	Error: . CHEMBL231421	3-NP	MIC	>	3361300.0	---	nM	---	---	CHEMBL886422	Growth inhibition of Magnaporthe grisea Guy 11 in presence of glucose after 6 days	organism-based format	Pyricularia grisea	CHEMBL612468	Pyricularia grisea	Pyricularia grisea	ORGANISM	CHEMBL1144623	Scientific Literature	---
2.	Error: . CHEMBL231421	3-NP	MIC	=	2941200.0	---	nM	---	---	CHEMBL886423	Growth inhibition of Magnaporthe grisea Guy 11 in presence of sodium acetate after 6 days	organism-based format	Pyricularia grisea	CHEMBL612468	Pyricularia grisea	Pyricularia grisea	ORGANISM	CHEMBL1144623	Scientific Literature	---
3.	Error: . CHEMBL231421	3-NP	IC50	=	1570200.0	---	nM	---	---	CHEMBL886420	Inhibition of Magnaporthe grisea Guy 11 malate synthase	assay format	Pyricularia grisea	CHEMBL612545	Unchecked	---	UNCHECKED	CHEMBL1144623	Scientific Literature	---
4.	Error: . CHEMBL231421	3-NP	IC50	=	92400.0	---	nM	4.03	---	CHEMBL886419	Inhibition of Magnaporthe grisea Guy 11 isocitrate lyase	single protein format	Pyricularia grisea	CHEMBL1075264	Isocitrate lyase	Magnaporthe oryzae (strain 70-15 / FGSC 8958) (Rice blast fungus)(Pyricularia oryzae)	SINGLE PROTEIN	CHEMBL1144623	Scientific Literature	---
5.	Error: . CHEMBL451226	3-NP	IC50	>	100000.0	---	nM	---	---	CHEMBL3300584	Inhibition of sortase A (unknown origin)	assay format	Not specified	CHEMBL612545	Unchecked	---	UNCHECKED	CHEMBL3297669	Scientific Literature	---
6.	Error: . CHEMBL451226	SID11111544	Potency	=	25118.9	---	nM	4.60	Inconclusive	CHEMBL1614456	PUBCHEM_BIOASSAY: qHTS Assay for Identification of Small Molecule Agonists for Hypoxia Response Element Signaling Pathway. (Class of assay: confirmatory) [Related pubchem assays: 915 ]	assay format	Homo sapiens	CHEMBL4261	Hypoxia-inducible factor 1 alpha	Homo sapiens	SINGLE PROTEIN	CHEMBL1201862	PubChem BioAssays	---
7.	Error: . CHEMBL451226	SID11111544	Potency	=	63.1	---	nM	7.20	Inconclusive	CHEMBL1613997	PUBCHEM_BIOASSAY: qHTS Assay for Antagonists of Acetylcholine Muscarinic M1 Receptor: Kinetic Measurement of Intracellular Calcium Response. (Class of assay: confirmatory)	assay format	Rattus norvegicus	CHEMBL276	Muscarinic acetylcholine receptor M1	Rattus norvegicus	SINGLE PROTEIN	CHEMBL1201862	PubChem BioAssays	---
8.	Error: . CHEMBL451226	3-NP	MIC	>	419920.0	---	nM	---	---	CHEMBL1820646	Antimycobacterial activity against active log phase Mycobacterium smegmatis ATCC 14468 by agar dilution method	organism-based format	Mycolicibacterium smegmatis	CHEMBL613088	Mycolicibacterium smegmatis	Mycolicibacterium smegmatis	ORGANISM	CHEMBL1817660	Scientific Literature	---
9.	Error: . CHEMBL451226	3-NP	MIC	>	1000000.0	---	nM	---	---	CHEMBL3363758	Antimycobacterial activity against Isoniazid, rifampicin, ofloxacin and ethambutol-resistant Mycobacterium avium 330/88 assessed as complete growth inhibition after 21 days	organism-based format	Mycobacterium avium	CHEMBL614982	Mycobacterium avium	Mycobacterium avium	ORGANISM	CHEMBL3352384	Scientific Literature	---
10.	Error: . CHEMBL451226	3-NP	MIC	>	1000000.0	---	nM	---	---	CHEMBL3363764	Antimycobacterial activity against clinical isolate Mycobacterium kansasii 6509/96 assessed as complete growth inhibition after 21 days	organism-based format	Mycobacterium kansasii	CHEMBL614984	Mycobacterium kansasii	Mycobacterium kansasii	ORGANISM	CHEMBL3352384	Scientific Literature	---
11.	Error: . CHEMBL451226	3-NP	IC50	=	53900.0	---	nM	4.27	---	CHEMBL2212269	Inhibition of Candida albicans ATCC 10231 isocitrate lyase by spectrophotometric analysis	single protein format	Candida albicans	CHEMBL5359	Isocitrate lyase	Candida albicans	SINGLE PROTEIN	CHEMBL2203252	Scientific Literature	---
12.	Error: . CHEMBL451226	3-Nitropropionate	MIC	=	200.0	---	ug.mL-1	---	---	CHEMBL2406165	Antifungal activity against Candida albicans SC5314 assessed as growth inhibition after 48 hrs in presence of 2% potassium acetate	organism-based format	Candida albicans	CHEMBL366	Candida albicans	Candida albicans	ORGANISM	CHEMBL2401674	Scientific Literature	---
13.	Error: . CHEMBL451226	3-Nitropropionate	IC50	=	13910.0	---	nM	4.86	---	CHEMBL2406167	Inhibition of recombinant Candida albicans ATCC 10231 ICL using phenylhydrazine and isocitrate as substrate assessed as formation of glyoxylate phenylhydrazone after 30 mins by spectrophotometric analysis	single protein format	Candida albicans	CHEMBL5359	Isocitrate lyase	Candida albicans	SINGLE PROTEIN	CHEMBL2401674	Scientific Literature	---
14.	Error: . CHEMBL451226	3-NP	Selectivity Index	<	0.7	---	---	---	---	CHEMBL3363781	Selectivity index, ratio of IC50 for human HepG2 cells to MIC for Mycobacterium tuberculosis H37Rv	cell-based format	---	CHEMBL612545	Unchecked	---	UNCHECKED	CHEMBL3352384	Scientific Literature	CHEMBL3307718
15.	Error: . CHEMBL451226	3-NP	MIC	>	1000000.0	---	nM	---	---	CHEMBL3363762	Antimycobacterial activity against clinical isolate Mycobacterium kansasii 6509/96 assessed as complete growth inhibition after 7 days	organism-based format	Mycobacterium kansasii	CHEMBL614984	Mycobacterium kansasii	Mycobacterium kansasii	ORGANISM	CHEMBL3352384	Scientific Literature	---
16.	Error: . CHEMBL451226	3-NP	MIC	>	100000.0	---	nM	---	---	CHEMBL3365855	Antimycobacterial activity against Mycobacterium tuberculosis H37Rv 331/88 assessed as complete growth inhibition after 14 days	organism-based format	Mycobacterium tuberculosis	CHEMBL360	Mycobacterium tuberculosis	Mycobacterium tuberculosis	ORGANISM	CHEMBL3352384	Scientific Literature	---
17.	Error: . CHEMBL451226	3-NP	CC50	<	524900.0	---	nM	---	---	CHEMBL1820653	Cytotoxicity against African green monkey Vero cells after 72 hrs by MTT assay	cell-based format	Chlorocebus sabaeus	CHEMBL391	Vero	Chlorocebus sabaeus	CELL-LINE	CHEMBL1817660	Scientific Literature	CHEMBL3307520
18.	Error: . CHEMBL451226	3-NP	MIC	>	419920.0	---	nM	---	---	CHEMBL1820647	Antimycobacterial activity against active log phase Mycobacterium tuberculosis H37Rv by agar dilution method	organism-based format	Mycobacterium tuberculosis	CHEMBL360	Mycobacterium tuberculosis	Mycobacterium tuberculosis	ORGANISM	CHEMBL1817660	Scientific Literature	---
19.	Error: . CHEMBL451226	SID90341292	Potency	---	39810.7	---	nM	---	inconclusive	CHEMBL1738442	PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Histone Lysine Methyltransferase G9a. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504404]	assay format	Homo sapiens	CHEMBL6032	Histone-lysine N-methyltransferase, H3 lysine-9 specific 3	Homo sapiens	SINGLE PROTEIN	CHEMBL1201862	PubChem BioAssays	---
20.	Error: . CHEMBL451226	SID47193673	Potency	---	562.3	---	nM	---	inconclusive	CHEMBL2354287	PubChem BioAssay. qHTS of TDP-43 Inhibitors. (Class of assay: confirmatory)	assay format	---	CHEMBL2362981	TAR DNA-binding protein 43	Homo sapiens	SINGLE PROTEIN	CHEMBL1201862	PubChem BioAssays	---

Showing 1-20 out of 95 records

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