Assays

43 items

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Per Property
28
A - ADME
7
B - Binding
4
F - Functional
4
P - Physicochemical
42
N/A
1
MUSCULO-SKELETAL SYSTEM
42
N/A
1
Anti-Inflammatory Activity
42
N/A
1
Croton Oil Ear Edema
1
General Anti-Inflammatory Models
35
Eukaryotes
7
N/A
1
Bacteria
32
Mammalia
7
N/A
2
Apicomplexa
1
Gram-Positive
1
Nematoda
27
Primates
7
N/A
5
Rodentia
2
Plasmodium
1
Mycobacterium
1
Rhabditida
27
Homo sapiens
7
N/A
3
Mus musculus
2
Plasmodium falciparum
1
Caenorhabditis elegans
1
Cricetulus griseus
1
Mycobacterium tuberculosis
1
Rattus norvegicus
25
single protein format
7
cell-based format
4
assay format
4
small-molecule physicochemical format
3
organism-based format
42
Scientific Literature
1
AstraZeneca DMPK/physicochemical
29
9 - Direct single protein target assigned
6
0 - Default value - Target unknown or has yet to be assigned
6
1 - Target assigned is non-molecular
1
4 - Multiple homologous protein targets may be assigned
1
8 - Homologous single protein target assigned
Showing 1-20 out of 43 records
#ChEMBL IDAssay TypeDescriptionOrganismCompoundsDocument ChEMBL IDBAO FormatSource
1.
CHEMBL2027501
P
Solubility of the compound in water
---
CHEMBL2021803
small-molecule physicochemical format
Scientific Literature
2.
CHEMBL1249495
B
Inhibition of human caspase-3-mediated apoptosis assessed as appearance of [35]S methionine-labeled PARP cleavage product at 100 uM after 2 hrs by fluorescence assay
Homo sapiens
CHEMBL1240309
single protein format
Scientific Literature
3.
CHEMBL1249494
B
Inhibition of Caenorhabditis elegans CED-3-mediated apoptosis assessed as [35]S methionine labeled CED-9 cleavage product at 100 uM after 2 hrs by fluorescence assay
Caenorhabditis elegans
CHEMBL1240309
single protein format
Scientific Literature
4.
CHEMBL1027395
B
Inhibition of human recombinant MK2 expressed in Escherichia coli BL21(DE3) after 60 mins
Homo sapiens
CHEMBL1140089
assay format
Scientific Literature
5.
CHEMBL1743335
A
Substrate of human UDP-glucuronosyltransferase UGT2B11
Homo sapiens
CHEMBL1743201
single protein format
Scientific Literature
6.
CHEMBL1743331
A
Substrate of human UDP-glucuronosyltransferase UGT1A10
Homo sapiens
CHEMBL1743201
single protein format
Scientific Literature
7.
CHEMBL1743327
A
Substrate of human UDP-glucuronosyltransferase UGT1A6
Homo sapiens
CHEMBL1743201
single protein format
Scientific Literature
8.
CHEMBL4201519
A
Cytotoxicity in human K562 cells assessed as reduction in cell viability incubated for 72 hrs by cell-QB reagent based assay
Homo sapiens
CHEMBL4196196
cell-based format
Scientific Literature
9.
CHEMBL3531466
A
Inhibition of human recombinant UGT1A1 expressed in HEK293 cells assessed as reduction in estradiol 3-glucuronidation by LC-MS/MS method
Homo sapiens
CHEMBL3526014
cell-based format
Scientific Literature
10.
CHEMBL3531465
A
Inhibition of human recombinant UGT1A1 expressed in HEK293 cells assessed as reduction in bilirubin glucuronidation by LC-MS/MS method
Homo sapiens
CHEMBL3526014
cell-based format
Scientific Literature
11.
CHEMBL1743309
A
Major substrate of human cytosolic sulfotransferase SULT1E1
Homo sapiens
CHEMBL1743201
single protein format
Scientific Literature
12.
CHEMBL3367391
F
Radioprotective activity against gamma-irradiated human MOLT4 cells preincubated for 1 hr at 100 to 400 uM before gamma-irradiation measured after 18 hrs by erythrosine B dye-exclusion test
Homo sapiens
CHEMBL3351457
cell-based format
Scientific Literature
13.
CHEMBL4222538
B
Inhibition of Mycobacterium tuberculosis IMPDH deltaCBS mutant assessed as reduction in NADH production at 1 mM using IMP as substrate preincubated for 5 mins followed by substrate addition measured for 32 mins in presence of NAD+
Mycobacterium tuberculosis
CHEMBL4219150
assay format
Scientific Literature
14.
CHEMBL767495
B
In vitro inhibition of Prostaglandin G/H synthase in BSV cell line.
---
CHEMBL1124955
cell-based format
Scientific Literature
15.
CHEMBL1932231
F
Antiplasmodial activity against chloroquine-sensitive Plasmodium falciparum D10 after 48 hrs by lactate dehydrogenase assay
Plasmodium falciparum
CHEMBL1926568
organism-based format
Scientific Literature
16.
CHEMBL1932232
F
Antiplasmodial activity against chloroquine-resistant Plasmodium falciparum K1 after 48 hrs by lactate dehydrogenase assay
Plasmodium falciparum
CHEMBL1926568
organism-based format
Scientific Literature
17.
CHEMBL1932277
A
Cytotoxicity against CHO cells after 48 hrs by MTT assay
Cricetulus griseus
CHEMBL1926568
cell-based format
Scientific Literature
18.
CHEMBL1908089
A
Specific activity of expressed human recombinant UGT2B10
Homo sapiens
CHEMBL1907987
single protein format
Scientific Literature
19.
CHEMBL1908088
A
Specific activity of expressed human recombinant UGT2A1
Homo sapiens
CHEMBL1907987
single protein format
Scientific Literature
20.
CHEMBL1023676
A
Inhibition of mouse CYP2A5
Mus musculus
CHEMBL1158374
single protein format
Scientific Literature
Showing 1-20 out of 43 records
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