Assays

301 items

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252
B - Binding
46
F - Functional
2
A - ADME
1
T - Toxicity
301
N/A
301
N/A
301
N/A
245
Eukaryotes
47
N/A
7
Bacteria
1
Fungi
1
Viruses
242
Mammalia
47
N/A
4
Gram-Positive
3
Gram-Negative
1
Ascomycota
1
Aves
1
Fornicata
1
Kinetoplastida
1
ssRNA
226
Primates
49
N/A
7
Rodentia
6
Lagomorpha
3
Escherichia
2
Bacillus
2
Cetartiodactyla
2
Other
1
Perissodactyla
1
Saccharomycetales
2
Other
225
Homo sapiens
47
N/A
6
Oryctolagus cuniculus
4
Rattus norvegicus
3
Escherichia coli
3
Mus musculus
2
Bos taurus
2
Thermus thermophilus
1
Bacillus anthracis str. A2012
1
Bacillus subtilis
7
Other
199
single protein format
58
assay format
32
cell-based format
4
protein complex format
4
tissue-based format
2
organism-based format
2
protein format
255
Scientific Literature
39
PubChem BioAssays
3
SARS-CoV-2 Screening Data
2
Fraunhofer Institute HDAC6 screening
1
EU-OPENSCREEN
1
SureChEMBL Patent Bioactivity Data
212
9 - Direct single protein target assigned
42
8 - Homologous single protein target assigned
21
0 - Default value - Target unknown or has yet to be assigned
16
1 - Target assigned is non-molecular
5
5 - Multiple direct protein targets may be assigned
3
7 - Direct protein complex subunits assigned
2
4 - Multiple homologous protein targets may be assigned
Showing 1-20 out of 301 records
#ChEMBL IDAssay TypeDescriptionOrganismCompoundsDocument ChEMBL IDBAO FormatSource
1.
CHEMBL4145875
B
Inhibition of HIPK1 (unknown origin)
Homo sapiens
CHEMBL4145442
single protein format
Scientific Literature
2.
CHEMBL920896
F
Increase in light chain 3-GFP+ autophagosome vesicle number per cell in human H4 cells at 4.5 uM after 24 hrs by high throughput fluorescence microscopy relative to control
Homo sapiens
CHEMBL1145471
cell-based format
Scientific Literature
3.
CHEMBL1776537
B
Inhibition of p70S6K at 1 uM
---
CHEMBL1773035
single protein format
Scientific Literature
4.
CHEMBL909381
B
Selectivity for SIRT2 over SIRT1
Homo sapiens
CHEMBL1137294
assay format
Scientific Literature
5.
CHEMBL1249814
B
Inhibition of His-tagged human GSK3b expressed in Sf21 cells
Homo sapiens
CHEMBL1240295
cell-based format
Scientific Literature
6.
CHEMBL4328287
B
Inhibition of human VRK2 assessed as residual activity at 100 uM using casein as substrate by [gamma-33P]-ATP assay relative to control
Homo sapiens
CHEMBL4325871
single protein format
Scientific Literature
7.
CHEMBL4328084
B
Inhibition of human HPK1 assessed as residual activity at 100 uM using MBP as substrate by [gamma-33P]-ATP assay relative to control
Homo sapiens
CHEMBL4325871
single protein format
Scientific Literature
8.
CHEMBL1776533
B
Inhibition of GSK3-beta at 1 uM
---
CHEMBL1773035
single protein format
Scientific Literature
9.
CHEMBL1776539
B
Inhibition of PKCalpha at 1 uM
---
CHEMBL1773035
single protein format
Scientific Literature
10.
CHEMBL3368448
B
Inhibition of PKCzeta (unknown origin) expressed in HEK293 cells assessed as reduction in specific activity at 2 to 5 uM for 6 hrs after 30 mins IGF-I stimulation by in serum free medium
Homo sapiens
CHEMBL3351692
cell-based format
Scientific Literature
11.
CHEMBL4328286
B
Inhibition of human VRK1 assessed as residual activity at 100 uM using KEAKEKRQEQIAKRRRLSSLRASTSKSGGSQK as substrate by [gamma-33P]-ATP assay relative to control
Homo sapiens
CHEMBL4325871
single protein format
Scientific Literature
12.
CHEMBL4328080
B
Inhibition of human HIPK1 assessed as residual activity at 100 uM using MBP as substrate by [gamma-33P]-ATP assay relative to control
Homo sapiens
CHEMBL4325871
single protein format
Scientific Literature
13.
CHEMBL1049695
B
Inhibition of SIRT2 in human MCF7 cells assessed as tubulin hyperacetylation at 10 uM after 16 hrs by Western blot
Homo sapiens
CHEMBL1156803
cell-based format
Scientific Literature
14.
CHEMBL1776592
F
Antiproliferative activity against human MDA-MB-231 cells over expressing RSK2 at 10 uM after 48 hrs by MTT assay
Homo sapiens
CHEMBL1773035
cell-based format
Scientific Literature
15.
CHEMBL1776545
F
Antiproliferative activity against human MCF7 cells over expressing RSK2 at 10 uM after 48 hrs by MTT assay
Homo sapiens
CHEMBL1773035
cell-based format
Scientific Literature
16.
CHEMBL1776538
B
Inhibition of PDK1 at 1 uM
---
CHEMBL1773035
single protein format
Scientific Literature
17.
CHEMBL1249815
B
Inhibition of His-tagged human PKCalpha expressed in Escherichia coli
Homo sapiens
CHEMBL1240295
assay format
Scientific Literature
18.
CHEMBL1776535
B
Inhibition of MSK1 at 1 uM
---
CHEMBL1773035
single protein format
Scientific Literature
19.
CHEMBL1776536
B
Inhibition of p38alpha at 1 uM
---
CHEMBL1773035
single protein format
Scientific Literature
20.
CHEMBL1776534
B
Inhibition of JNK1 at 1 uM
---
CHEMBL1773035
single protein format
Scientific Literature
Showing 1-20 out of 301 records
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