Assays
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| # | ChEMBL ID | Assay Type | Description | Organism | Compounds | Document ChEMBL ID | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. |
B
|
Selectivity ratio of IC50 for human recombinant full length C-terminal His-tagged chitotriosidase to IC50 for human recombinant full length C-terminal His-tagged acidic mammalian chitinase
|
Homo sapiens
|
assay format
|
Scientific Literature
| ||||
| 2. |
B
|
Inhibition of full length recombinant C-terminal His-taged human CHIT1 expressed in CHOK1 cells assessed as reduction in chitinolytic activity using 4-methylumbelliferyl-beta-D-N,N',N''-diacetylchitotrioside as substrate incubated for 60 mins under shaking condition by microplate fluorometry analysis
|
Homo sapiens
|
cell-based format
|
Scientific Literature
| ||||
| 3. |
B
|
Inhibition of full length recombinant C-terminal His-tagged human acidic mammalian chitinase expressed in CHOK1 cells assessed as reduction in chitinolytic activity using 4-methylumbelliferyl-beta-D-N,N-diacetylchitobioside hydrate as substrate incubated for 60 mins under shaking condition by microplate fluorometry analysis
|
Homo sapiens
|
cell-based format
|
Scientific Literature
| ||||
| 4. |
B
|
Inhibition of mouse recombinant full length C-terminal His-tagged acidic mammalian chitinase expressed in CHO-K1 cells using 4-methylumbelliferyl-beta-D-N,N'-diacetylchitobioside hydrate as substrate after 60 mins by fluorescence assay
|
Mus musculus
|
cell-based format
|
Scientific Literature
| ||||
| 5. |
B
|
Inhibition of human recombinant full length C-terminal His-tagged chitotriosidase expressed in CHO-K1 cells using 4-methylumbelliferyl-beta-D-N,N',N\"\"-triacetylchitotrioside as substrate after 60 mins by fluorescence assay
|
Homo sapiens
|
cell-based format
|
Scientific Literature
| ||||
| 6. |
B
|
Selectivity index, ratio of IC50 for full length recombinant C-terminal His-taged human CHIT1 using 4-methylumbelliferyl-beta-D-N,N',N''-diacetylchitotrioside as substrate incubated for 60 mins under shaking condition by microplate fluorometry analysis to IC50 recombinant C-terminal His-tagged human acidic mammalian chitinase using 4-methylumbelliferyl-beta-D-N,N-diacetylchitobioside hydrate as substrate incubated for 60 mins under shaking condition by microplate fluorometry analysis
|
Homo sapiens
|
assay format
|
Scientific Literature
| ||||
| 7. |
B
|
Inhibition of human recombinant full length C-terminal His-tagged acidic mammalian chitinase expressed in CHO-K1 cells using 4-methylumbelliferyl-beta-D-N,N'-diacetylchitobioside hydrate as substrate after 60 mins by fluorescence assay
|
Homo sapiens
|
cell-based format
|
Scientific Literature
| ||||
| 8. |
B
|
Inhibition of mouse recombinant full length C-terminal His-tagged chitotriosidase expressed in CHO-K1 cells using 4-methylumbelliferyl-beta-D-N,N',N\"\"-triacetylchitotrioside as substrate after 60 mins by fluorescence assay
|
Mus musculus
|
cell-based format
|
Scientific Literature
|
Showing 1-8
out of 8 records
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