Assays

94 items

Tools
Filters
Custom
Per Property
54
F - Functional
36
B - Binding
2
A - ADME
1
T - Toxicity
1
U - Unassigned
94
N/A
94
N/A
94
N/A
30
Fungi
28
Bacteria
22
Eukaryotes
14
N/A
30
Ascomycota
28
Gram-Positive
22
Mammalia
14
N/A
28
Mycobacterium
18
Saccharomycetales
17
Primates
14
N/A
9
Sordariomycetes
4
Rodentia
3
Eurotiomycetes
1
Cetartiodactyla
18
Candida albicans
14
Homo sapiens
14
Mycobacterium tuberculosis
13
N/A
8
Pyricularia grisea
6
Mycobacterium kansasii
4
Mycobacterium tuberculosis H37Rv
3
Chlorocebus sabaeus
3
Rattus norvegicus
2
Mycobacterium avium
9
Other
37
assay format
28
organism-based format
17
single protein format
11
cell-based format
1
tissue-based format
72
Scientific Literature
21
PubChem BioAssays
1
IMI-CARE SARS-CoV-2 Data
34
1 - Target assigned is non-molecular
26
9 - Direct single protein target assigned
17
0 - Default value - Target unknown or has yet to be assigned
16
8 - Homologous single protein target assigned
1
5 - Multiple direct protein targets may be assigned
Showing 1-20 out of 94 records
#ChEMBL IDAssay TypeDescriptionOrganismCompoundsDocument ChEMBL IDBAO FormatSource
1.
CHEMBL886420
B
Inhibition of Magnaporthe grisea Guy 11 malate synthase
Pyricularia grisea
CHEMBL1144623
assay format
Scientific Literature
2.
CHEMBL1006070
F
Cytotoxicity against human KB cells at 167.9 uM
Homo sapiens
CHEMBL1141756
cell-based format
Scientific Literature
3.
CHEMBL1664816
B
Inhibition of Mycobacterium tuberculosis isocitrate lyase at 100 mM
Mycobacterium tuberculosis
CHEMBL1649368
single protein format
Scientific Literature
4.
CHEMBL1006066
F
Cytotoxicity against human NCI-H187 cells at 167.9 uM
Homo sapiens
CHEMBL1141756
cell-based format
Scientific Literature
5.
CHEMBL1006072
F
Cytotoxicity against african green monkey Vero cells at 419.8 uM
Chlorocebus sabaeus
CHEMBL1141756
cell-based format
Scientific Literature
6.
CHEMBL886419
B
Inhibition of Magnaporthe grisea Guy 11 isocitrate lyase
Pyricularia grisea
CHEMBL1144623
single protein format
Scientific Literature
7.
CHEMBL886422
F
Growth inhibition of Magnaporthe grisea Guy 11 in presence of glucose after 6 days
Pyricularia grisea
CHEMBL1144623
organism-based format
Scientific Literature
8.
CHEMBL886423
F
Growth inhibition of Magnaporthe grisea Guy 11 in presence of sodium acetate after 6 days
Pyricularia grisea
CHEMBL1144623
organism-based format
Scientific Literature
9.
CHEMBL941486
B
Induction of REST/NRSF-coupled repression of luciferase tagged rat RE1/NRSE BDNF promoter activity expressed in ST14A cells at 5 nM assessed as increase in luciferase activity
Rattus norvegicus
CHEMBL1156478
cell-based format
Scientific Literature
10.
CHEMBL1211896
B
Percent inhibition of Mycobacterium tuberculosis isocitrate lyase (ICL) at 100 uM
Mycobacterium tuberculosis
CHEMBL1208755
single protein format
Scientific Literature
11.
CHEMBL1006068
F
Cytotoxicity against human BC cells at 167.9 uM
Homo sapiens
CHEMBL1141756
cell-based format
Scientific Literature
12.
CHEMBL941487
B
Induction of REST/NRSF-coupled repression of luciferase tagged rat RE1/NRSE BDNF promoter activity expressed in ST14A cells at 10 nM assessed as increase in luciferase activity
Rattus norvegicus
CHEMBL1156478
cell-based format
Scientific Literature
13.
CHEMBL3366401
B
Inhibition of Candida albicans ATCC 10231 isocitrate lyase
Candida albicans
CHEMBL3352126
single protein format
Scientific Literature
14.
CHEMBL1006065
F
Antimycobacterial activity against Mycobacterium tuberculosis H37Ra by microplate alamar blue assay
Mycobacterium tuberculosis
CHEMBL1141756
organism-based format
Scientific Literature
15.
CHEMBL4258185
B
Binding affinity to Mycobacterium tuberculosis ICL1 expressed in Escherichia coli BL21(DE3) assessed as melting temperature at 1 mM in presence of MgCl2 by SYPRO orange dye based fluorescence assay (Rvb = 43 degC)
Mycobacterium tuberculosis
CHEMBL4257464
assay format
Scientific Literature
16.
CHEMBL3374059
B
Inhibition of Candida albicans isocitrate lyase using isocitrate substrate
Candida albicans
CHEMBL3351291
assay format
Scientific Literature
17.
CHEMBL2091659
B
Inhibition of Mycobacterium tuberculosis H37Rv isocitrate lyase expressed in Escherichia coli BL21(DE3) using (+)-potassium Ds-threo-isocitrate as substrate assessed as glyoxylate phenyl hydrazone formation at 100 umol/L by spectrophotometry
Mycobacterium tuberculosis H37Rv
CHEMBL2086318
assay format
Scientific Literature
18.
CHEMBL1943009
B
Inhibition of isocitrate lyase
---
CHEMBL1938237
assay format
Scientific Literature
19.
CHEMBL4258182
B
Inhibition of Mycobacterium tuberculosis ICL1 expressed in Escherichia coli BL21(DE3) using DL-isocitrate as substrate incubated for 25 mins in presence of MgCl2 by 1H NMR method
Mycobacterium tuberculosis
CHEMBL4257464
assay format
Scientific Literature
20.
CHEMBL2212269
B
Inhibition of Candida albicans ATCC 10231 isocitrate lyase by spectrophotometric analysis
Candida albicans
CHEMBL2203252
single protein format
Scientific Literature
Showing 1-20 out of 94 records
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