MDCK-MDR1


ID: CHEMBL4295482
Name: MDCK-MDR1
Description: MDCK-MDR1
Source tissue: Kidney
Source organism: Canis lupus familiaris
Source tax ID: 9615
Cell Line Ontology: ---
Experimental Factor Ontology: ---
Cellosaurus: CVCL_S586
LINCS Project: ---
Assay Summary
A - ADME
Total
533
A - ADME
B - Binding
F - Functional
Associated Bioactivities
Ratio Papp permeability
Total
3896
Ratio
Papp
permeability
Papp A to B (mean)
Recovery A to B (mean)
EC50
Inhibition
Drug recovery
Activity
Efflux ratio
Efflux ratio plus inhibitor
Papp A to B plus inhibitor (mean)
Papp B to A (mean)
Papp B to A plus inhibitor (mean)
Recovery A to B plus inhibitor (mean)
Recovery B to A (mean)
Recovery B to A plus inhibitor (mean)
Drug transport
Drug uptake
IC50
Histogram Settings


169.5 339 508.5 678 847.5 1,017 [0.00, 145.18) [145.18, 290.36) [290.36, 435.54) [435.54, 580.72) [580.72, 725.91) [725.91, 871.09) [871.09, 1016.27) [1016.27, 1161.45) [1161.45, 1306.63) [1306.63, 1451.81) [1451.81, 1482.57]
Total
2035
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