Synopsis of some recent tactical application of bioisosteres in drug design.
ID: CHEMBL2203023
Journal: J Med Chem
Title: Synopsis of some recent tactical application of bioisosteres in drug design.
Authors: Meanwell NA.
Abstract:
CiteXplore: 21413808
DOI: 10.1021/jm1013693
Patent ID: ---
Protein Target Summary
Total
54
Eukaryotes
Viruses
N/A
Assay Summary
Total
80
B - Binding
F - Functional
A - ADME
P - Physicochemical
Bioactivity Summary
Total
367
IC50
Ki
EC50
CL
pKa
LogP
T1/2
permeability
Km
LogD
Vmax
Vmax/Km
Solubility
Inhibition
EC90
Activity
ED50
INH
Kd
Papp
Other