Synopsis of some recent tactical application of bioisosteres in drug design.


ID: CHEMBL2203023
Journal: J Med Chem
Title: Synopsis of some recent tactical application of bioisosteres in drug design.
Authors: Meanwell NA.
Abstract:
CiteXplore: 21413808
Patent ID: ---
Assay Summary
B - Binding F - Func... A - ADME P - Phys...
Total
80
B - Binding
F - Functional
A - ADME
P - Physicochemical
Bioactivity Summary
IC50 Ki EC50 CL pKa
Total
367
IC50
Ki
EC50
CL
pKa
LogP
T1/2
permeability
Km
LogD
Vmax
Vmax/Km
Solubility
Inhibition
EC90
Activity
ED50
INH
Kd
Papp
Other
Histogram Settings


10.33 20.67 31 41.33 51.67 62 [0.00, 90.94) [90.94, 181.88) [181.88, 272.81) [272.81, 363.75) [363.75, 454.69) [454.69, 545.63) [545.63, 636.57) [636.57, 727.51) [727.51, 818.44) [818.44, 909.38) [909.38, 930.96]
Total
213
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