Solute carrier organic anion transporter family member 1B1
ID: CHEMBL1697668
Type: SINGLE PROTEIN
Preferred Name: Solute carrier organic anion transporter family member 1B1
Synonyms:
Liver-specific organic anion transporter 1
LST-1
LST1
OATP1B1
OATP-2
Synonyms: ---
organism: Homo sapiens
Species Group: No
Protein Target Classification:
1.
| Description | Relationship | Accession |
|---|---|---|
| Solute carrier organic anion transporter family member 1B1 | SINGLE PROTEIN | Q9Y6L6 |
| ChEMBL ID | Relationship | Pref Name | Target Type |
|---|---|---|---|
| CHEMBL3885536 | SUPERSET OF | Canalicular multispecific organic anion transporter 1/Solute carrier organic anion transporter family member 1B1 | PROTEIN FAMILY |
Associated Bioactivities
Total
2675
Inhibition
IC50
Activity
Ki
Km
FC
Ratio
Drug uptake
EC50
Vmax
INH
Vmax/Km
pXC50
Associated Assays
Total
221
F - Functional
A - ADME
B - Binding
See all activities used in this plot (20)
Ligand Efficiencies for Target CHEMBL1697668 (Solute carrier organic anion transporter family member 1B1)
Standard Value nM
<1
(0 items)
[1,100)
(0 items)
[100,1000)
(0 items)
>=1000
(12 items)
Showing 12 data points.
Hover over a point to see the details.
The Ligand Efficiency chart plots Binding Efficiency Index (BEI)
against Surface Efficiency Index (SEI), where:
- SEI = (-log10(Standard Value*10^-9))*100/PSA
- BEI = (-log10(Standard Value*10^-9))*1000/MWT
- GO:0005886 (plasma membrane)
- GO:0009925 (basal plasma membrane)
- GO:0016020 (membrane)
- GO:0016323 (basolateral plasma membrane)
- GO:0008514 (organic anion transmembrane transporter activity)
- GO:0015125 (bile acid transmembrane transporter activity)
- GO:0015132 (prostaglandin transmembrane transporter activity)
- GO:0015347 (sodium-independent organic anion transmembrane transporter activity)
- GO:0022857 (transmembrane transporter activity)
- GO:0006805 (xenobiotic metabolic process)
- GO:0006811 (monoatomic ion transport)
- GO:0006869 (lipid transport)
- GO:0015711 (organic anion transport)
- GO:0015721 (bile acid and bile salt transport)
- GO:0015732 (prostaglandin transport)
- GO:0042167 (heme catabolic process)
- GO:0043252 (sodium-independent organic anion transport)
- GO:0055085 (transmembrane transport)
- GO:0070327 (thyroid hormone transport)
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