Serine/threonine-protein kinase PAK7
ID: CHEMBL4524
Type: SINGLE PROTEIN
Preferred Name: Serine/threonine-protein kinase PAK7
Synonyms:
KIAA1264
p21-activated kinase 5
p21-activated kinase 7
PAK-5
PAK5
Synonyms: ---
organism: Homo sapiens
Species Group: No
Protein Target Classification:
1.
| Description | Relationship | Accession |
|---|---|---|
| Serine/threonine-protein kinase PAK 5 | SINGLE PROTEIN | Q9P286 |
Associated Bioactivities
Total
1765
Inhibition
Residual Activity
Activity
Thermal melting change
Kd
% Control
IC50
Residual activity
Residual_activity
% Activity remaining
% Ctrl
% residual kinase activity
% Residual activity with Skepinone-L
Ki
Associated Assays
Total
162
B - Binding
See all activities used in this plot (38)
Ligand Efficiencies for Target CHEMBL4524 (Serine/threonine-protein kinase PAK7)
Standard Value nM
<1
(0 items)
[1,100)
(14 items)
[100,1000)
(12 items)
>=1000
(10 items)
Showing 36 data points.
Hover over a point to see the details.
The Ligand Efficiency chart plots Binding Efficiency Index (BEI)
against Surface Efficiency Index (SEI), where:
- SEI = (-log10(Standard Value*10^-9))*100/PSA
- BEI = (-log10(Standard Value*10^-9))*1000/MWT
- GO:0005634 (nucleus)
- GO:0005654 (nucleoplasm)
- GO:0005737 (cytoplasm)
- GO:0005739 (mitochondrion)
- GO:0005829 (cytosol)
- GO:0005886 (plasma membrane)
- GO:0031965 (nuclear membrane)
- GO:0045202 (synapse)
- GO:0005515 (protein binding)
- GO:0005524 (ATP binding)
- GO:0001558 (regulation of cell growth)
- GO:0006915 (apoptotic process)
- GO:0007010 (cytoskeleton organization)
- GO:0007165 (signal transduction)
- GO:0007612 (learning)
- GO:0007613 (memory)
- GO:0007626 (locomotory behavior)
- GO:0008283 (cell population proliferation)
- GO:0009267 (cellular response to starvation)
- GO:0016477 (cell migration)
- GO:0035556 (intracellular signal transduction)
- GO:0043408 (regulation of MAPK cascade)
- GO:2001237 (negative regulation of extrinsic apoptotic signaling pathway)
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