Mitogen-activated protein kinase 6
ID: CHEMBL5121
Type: SINGLE PROTEIN
Preferred Name: Mitogen-activated protein kinase 6
Synonyms:
ERK-3
ERK3
Extracellular signal-regulated kinase 3
MAPK 6
MAPK6
Synonyms: ---
organism: Homo sapiens
Species Group: No
Protein Target Classification:
1.
| Description | Relationship | Accession |
|---|---|---|
| Mitogen-activated protein kinase 6 | SINGLE PROTEIN | Q16659 |
Associated Bioactivities
Total
590
Kd
Thermal melting change
% Control
IC50
Activity
% of control
Inhibition
Tm
% of inhibition
% binding
Delta TM
Associated Assays
Total
83
B - Binding
See all activities used in this plot (104)
Ligand Efficiencies for Target CHEMBL5121 (Mitogen-activated protein kinase 6)
Standard Value nM
<1
(0 items)
[1,100)
(13 items)
[100,1000)
(35 items)
>=1000
(56 items)
Showing 104 data points.
Hover over a point to see the details.
The Ligand Efficiency chart plots Binding Efficiency Index (BEI)
against Surface Efficiency Index (SEI), where:
- SEI = (-log10(Standard Value*10^-9))*100/PSA
- BEI = (-log10(Standard Value*10^-9))*1000/MWT
- GO:0005634 (nucleus)
- GO:0005654 (nucleoplasm)
- GO:0005737 (cytoplasm)
- GO:0005829 (cytosol)
- GO:0032156 (septin cytoskeleton)
- GO:0032991 (protein-containing complex)
- GO:0005515 (protein binding)
- GO:0005524 (ATP binding)
- GO:0019901 (protein kinase binding)
- GO:0046982 (protein heterodimerization activity)
- GO:0000165 (MAPK cascade)
- GO:0006468 (protein phosphorylation)
- GO:0007165 (signal transduction)
- GO:0007254 (JNK cascade)
- GO:0035556 (intracellular signal transduction)
- GO:0060999 (positive regulation of dendritic spine development)
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