Purine-nucleoside phosphorylase
ID: CHEMBL2395
Type: SINGLE PROTEIN
Preferred Name: Purine-nucleoside phosphorylase
Synonyms:
Inosine-guanosine phosphorylase
Inosine phosphorylase
Np
Pnp
PNP
Synonyms: ---
organism: Rattus norvegicus
Species Group: No
Protein Target Classification:
1.
Description | Relationship | Accession |
---|---|---|
Purine nucleoside phosphorylase | SINGLE PROTEIN | P85973 |
Associated Bioactivities
Total
70
Ratio
IC50
Ki
Associated Assays
Total
7
B - Binding
See all activities used in this plot (30)
Ligand Efficiencies for Target CHEMBL2395 (Purine-nucleoside phosphorylase)
Standard Value nM
<1
[1,100)
[100,1000)
>=1000
Histogram Settings
Total
34
- GO:0005576 (extracellular region)
- GO:0005737 (cytoplasm)
- GO:0001882 (nucleoside binding)
- GO:0002060 (purine nucleobase binding)
- GO:0003824 (catalytic activity)
- GO:0004731 (purine-nucleoside phosphorylase activity)
- GO:0016740 (transferase activity)
- GO:0016757 (glycosyltransferase activity)
- GO:0016763 (pentosyltransferase activity)
- GO:0042301 (phosphate ion binding)
- GO:0042802 (identical protein binding)
- GO:0047975 (guanosine phosphorylase activity)
- GO:0000255 (allantoin metabolic process)
- GO:0006139 (nucleobase-containing compound metabolic process)
- GO:0006148 (inosine catabolic process)
- GO:0006149 (deoxyinosine catabolic process)
- GO:0006157 (deoxyadenosine catabolic process)
- GO:0006166 (purine ribonucleoside salvage)
- GO:0006204 (IMP catabolic process)
- GO:0006738 (nicotinamide riboside catabolic process)
- GO:0006955 (immune response)
- GO:0009116 (nucleoside metabolic process)
- GO:0009165 (nucleotide biosynthetic process)
- GO:0009410 (response to xenobiotic stimulus)
- GO:0032743 (positive regulation of interleukin-2 production)
- GO:0034418 (urate biosynthetic process)
- GO:0042102 (positive regulation of T cell proliferation)
- GO:0043101 (purine-containing compound salvage)
- GO:0046059 (dAMP catabolic process)
- GO:0046638 (positive regulation of alpha-beta T cell differentiation)
No cross references found.